Also found in: Thesaurus, Medical, Wikipedia.
Related to aztreonam: gentamicin


A synthetic antibiotic, C13H17N5O8S2, that acts against a wide spectrum of gram-negative bacteria.

[Variant of azthreonam : az(o)- + threon(ine) (used as a template for the antibiotic's chirality) + (beta-lact)am.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aztreonam - an antibiotic (trade name Azactam) used against severe infections; has minimal side effects
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
References in periodicals archive ?
Antibiotics MIC ([micro]g/mL) Susceptibility (a) Amikacin [greater than or R equal to] 64 Aztreonam 4 S Cefepime 8 S Ceftazidime [less than or S equal to] 1 Ciprofloxacin 2 I Gentamicin [greater than or R equal to] 16 Imipenem 1 S Meropenem 0.
For 10 days, the patient was given vancomycin (1 g/d), aztreonam (2 g/8 h), and metronidazole (500 mg/8 h).
6] The antibiotic discs used were Ampicillin (10[micro]g), Amikacin (30[micro]g), Cotrimoxazole (25[micro]g), Gentamicin (10[micro]g), Norfloxacin (10[micro]g), Nalidixic Acid (30[micro]g), Nitrofurantoin (300[micro]g), Ciprofloxacin (5[micro]g), Cefotaxime (30[micro]g), Ceftazidime (30[micro]g), Ceftriaxone (30[micro]g), Aztreonam (30[micro]), Imipinem (10[micro]).
Con el fin de conocer la sensibilidad a carbapenems (imipenem y meropenem), ceftazidime y aztreonam como indicadores fenotipicos de sustratos de [beta]-lactamasas, se analizaron 30 cepas de Pseudomonas aeruginosa (18 de muestras clinicas animales y 12 de aguas no clorinadas).
The isolates were found susceptible to imipenem, had intermediate susceptibility or were resistant to ceftazidime and cefepime, and were resistant to ampicillin, aztreonam, cefotaxime, ceftriaxone, chloramphenicol, ciprofloxacin, nalidixic acid, streptomycin, sulfisoxazole, tetracycline, and trimethoprim/sulfamethoxazole.
In two identically designed multinational, double-blind, noninferiority phase III studies of almost 1,400 patients with a variety of cSSSI, patients were randomized to treatment with ceftaroline monotherapy (at the proposed dose for 5-14 days), or vancomycin (1 g IV every 12 hours) plus aztreonam (1 g IV every 12 hours) for 5-14 days.
Los antimicrobianos ensayados fueron: piperacilina tazobactam (100/10 [micron]g), cefotaxima (30 [micron]g), ceftazidima (30 [micron]g), ceftriaxona (30 [micron]g), aztreonam (30 [micron]g), imipenem (10 [micron]g), amikacina (30 [micron]g), kanamicina (30 [micron]g), tobramicina (30 [micron]g), cefoxitin (30 [micron]g), cefepima (30 [micron]g), gentamicina (10 [micron]g), tetraciclina (30 [micron]g), cloranfenicol (30 [micron]g), ciprofloxacina (5 [micron]g) y amoxacilina/acido clavulanico (2:1) (30 [micron]g).
All the MBL positive isolates were repeatedly checked for reproducibility and for susceptibility with aztreonam.
The Food and Drug Administration refused to approve the biotech company's experimental cystic fibrosis drug, aztreonam lysine.
5) To be considered an ESBL, the organisms must be able to break down third and fourth generation cephalosporins (cefotaxime, ceftriaxone, cefepime, and ceftazidime) as well as aztreonam.
10,11) The enzymes created by these mutations became the ES[beta]Ls, and they are known to confer resistance to all penicillins, cephalosporins, and aztreonam.