beta-lactamase

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Related to b-lactamase: ESBL

be·ta-lac·ta·mase

 (bā′tə-lăk′tə-mās′, -māz′, bē′-)
n.
Any of various enzymes that hydrolyze and inactivate beta-lactam antibiotics such as penicillin, found in many antibiotic-resistant bacteria.

[beta-lactam, cyclic amide occurring in penicillins (beta + lact(one) + am(ide)) + -ase.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.beta-lactamase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Translations

be·ta-lac·ta·mase

a. beta-lactamasa, enzima que destruye el conjunto de beta-lactam antibióticos penicílicos haciéndolos no efectivos;
beta-lactamase resistanceresistencia de beta-lactamasa, a algunos tipos de penicilina.
References in periodicals archive ?
Plasmid-mediated carbapenem-hydrolyzing b-lactamase, KPC-2, in Klebsiella pneumoniae isolates.
Genetic environment and expression of the extended-spectrum b-lactamase blaPER-1 gene in gram-negative bacteria.
Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum B-lactamase encoded by an Escherichia coli integron gene.
Two different b-lactamase inhibitors (ethylenediaminetetraacetic acid [EDTA] and boronic acid) were used for the evaluation of class A and B production.
Dominance of CTX-M-type extended-spectrum b-lactamase (ESBL)-producing Escherichia coli isolated from patients with community-onset and hospital-onset infection in China.
Moreover, the b-lactamase inhibitors such as clavulanic acid or tazobactam can reduce the minimal inhibitory concentration (MIC) of drugs.
Prevalence and molecular characterization of extendedspectrum b-lactamase producing Klebsiella pneumoniae in Riyadh, Saudi Arabia.
Objective: The objective of this study was to determine the occurrence and antimicrobial profile of AmpC b-lactamase producing bacteria.
SHV-type extended-spectrum b-lactamase in a Shigella flexneri clinical isolate.
It consists of ceftazidime, a thirdgeneration cephalosporin, and avibactam, a non-B lactam B-lactamase inhibitor.
We believe that blood cultures should always be taken in cases of pneumonia and that the ability of this organism to produce B-lactamase and its potential to produce a fatal outcome should warn us that this is a pathogen that should not be underrated despite its low occurrence rate.
Characterization of a novel Amp C B-lactamase produced by carbapenem-resistant Cedecea davisae clinical isolate.