Against this backdrop, a recent study published in the Journal of the American Medical Association (JAMA) concluded that administration of cranberry capsules daily for one year had no significant effect on the presence of
bacteriuria plus pyuria in elderly women living in nursing homes.
Bacteriuria is defined as the presence of 10 (5) colony forming units (ie, viable bacteria) per milliliter of urine collected midstream on 2 consecutive urinations.
[17]
Bacteriuria is more common in diabetics than in non-diabetics due to a combination of host and local risk factors.
The authors tested the effect of two oral cranberry capsules daily on the presence of
bacteriuria plus pyuria among 185 women aged >65 years with or without
bacteriuria plus pyuria living in nursing homes using a double-blind, randomised, placebo-controlled efficacy trial over 1 year.
(1,7) For these kind of procedures, the main complications are
bacteriuria, urinary infection and, more rarely, bacteremia and sepsis.
"This trial did not show a benefit of cranberry capsules in terms of lower presence of
bacteriuria plus pyuria [presence of bacteria and white blood cells in the urine, a telltale sign of a UTI among older women living in nursing homes," the study stated.
Essas infeccoes podem ser agrupadas em quatro entidades clinicas diferentes, de acordo com a localizacao anatomica do agravo, mantendo, todavia, relacoes entre as mesmas:
bacteriuria assintomatica (BA), uretrite, cistite e pielonefrite (DUARTE et al., 2008).
GlobalData's clinical trial report, "
Bacteriuria Global Clinical Trials Review, H1, 2016" provides an overview of
Bacteriuria clinical trials scenario.
Essentially, residents who are not exhibiting symptoms of a UTI should not even be cultured, however, if they are, treatment with antibiotics needs to be thought out carefully as asymptomatic
bacteriuria results in a lot of unnecessary antibiotic use.
to rigorously screen patients for asymptomatic
bacteriuria, which can lead to pyelonephritis.