barbituric acid


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bar·bi·tu·ric acid

 (bär′bĭ-to͝or′ĭk, -tyo͝or′-)
n.
An acidic pyrimidine derivative, C4H4O3N2, used in the manufacture of barbiturates and some plastics.

[Partial translation of German Barbitursäure (coined by German chemist Adolf von Baeyer (1835-1917), purportedly after he discovered the compound on December 4, 1864, the feast of Saint Barbara, by combining malonic acid and urea) : Barbit- (irregularly derived from the name Barbara) + New Latin ūr(ea), urea; see urea + German Säure, acid.]

barbituric acid

(ˌbɑːbɪˈtjʊərɪk)
n
(Elements & Compounds) a white crystalline solid used in the preparation of barbiturate drugs. Formula: C4H4N2O3. Systematic name: 2,4,6-trioxypyrimidine Also called: malonylurea
[C19: partial translation of German Barbitursäure, perhaps from the name Barbara + uric + Säure acid]

bar′bitu′ric ac′id

(ˈbɑr bɪˈtʊər ɪk, -ˈtyʊər-, ˌbɑr-)
n.
a white, crystalline, slightly water-soluble powder, C4H4N2O3, used chiefly in the synthesis of barbiturates.
[1865–70; < French barbiturique < German Barbitur(säure) barbituric acid (of uncertain orig.) + -ique -ic]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.barbituric acid - a white crystalline acid derived from pyrimidinebarbituric acid - a white crystalline acid derived from pyrimidine; used in preparing barbiturate drugs
acid - any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
Translations
References in periodicals archive ?
Barbituric acid and its derivatives are associated with a number of biological activities such as antibacterial, hypotensive and sedative.
Hydroxymethylfurfural (HMF): It was determined by the AOAC method (958.09) where the absorbance of a filtered honey solution, after clarification with carrez solutions and addition of p-toluidine and barbituric acid solutions, is measured at 284 and 336 nm against a blank in the maximum color intensity (3-4 minutes after the barbituric acid addition) (Bogdanov et al., 2002).
These include barbituric acid, many phenols, ethanol, and a number of pesticides to name a few.
In the second tube was poured 2 ml of honey solution (10g/50 ml), 5 ml of reagent to para-toluidine (10g of para-toluidine dissolved in 50 ml of isopropanol and then 10 ml of glacial acetic acid and complete up to the mark of 100 ml with isopropanol) and 1 ml barbituric acid solution (500 mg of barbituric acid dissolved in 100 ml distilled water).
We then applied this solution to a test strip containing a barbituric acid derivative (H.
Oxidative damage is evaluated by a TBARS biochemical test (types that react to barbituric acid), and reflects the lipid peroxidation that affects the membrane due to the impact not only of the ethanol in the blood but also of the acetaldehyde produced by the action of the enzyme on the ethanol.
It was reported that free radical polymerization of BMI can be initiated by barbituric acid (BTA) (7) or 2,2'-azobisisobutyronitrile (AIBN) (8).
Thio Barbituric Acid Reactive Substances-(TBARS) assay is a simple reproducible and standardized procedure for assaying lipid peroxidation in plasma, serum, urine, tissue homogenates, and cell lysates.
One of the oldest groups of sedative drugs, the barbiturates, is a derivative of barbituric acid. Because of their toxic potential and rapid development of tolerance, they have largely been replaced by the benzodiazepines, except for a few specialized uses.
Transformation of barbituric acid into alloxan by hydroxyl radicals: Interaction with melatonin and with other hydroxyl radical scavengers.
The principle of the method depends on measurement of the pink color produced by interaction of the barbituric acid with MDA elaborated as a result of lipid peroxidation.