However, few studies have rigorously assessed basophilia
Ph + AML was defined as cases fulfilling the current WHO criteria for AML that bore the t(9;22)(q34;q11) or variant (9;22) translocation on bone marrow cytogenetics, had no history of chronic or accelerated phase chronic myeloid leukemia (CML) before diagnosis, no evidence of a CML-like picture following therapy for AML, no presence of splenomegaly or basophilia
(defined as >2% of basophils in peripheral blood) suggestive of a myeloproliferative neoplasm, and no history of chemotherapy and/or radiation therapy.,, Cases fulfilling diagnostic criteria of the 2016 WHO classification for acute ambiguous lineage leukemia were also excluded from the study.
and acidophilia depend on the amount of ribosomes in the cytoplasm; for this reason, cells with few ribosomes are acidophilic or eosinophilic (because of their affinity to eosin), and cells with many ribosomes are basophilic (Kuhnel 2005).
Fine needle aspirate was collected from various growths for cytological examination, which revealed large round cells with intracytoplasmic vacuolation, cytoplasmic basophilia
, round nuclei with prominent nucleoli and few mitotic figures (Fig.
De novo CD5 diffuse large B cell lymphoma with basophilia
in the peripheral blood: Successful treatment with autologous peripheral blood stem cell transplantation.
Right ear lobe biopsy was done and showed a mixed inflammatory infiltrate of the perichondrium composed of plasma cells, lymphocytes, histiocytes and neutrophils, and loss of the cartilage basophilia
. GMS and AFB were negative for fungal and mycobacterial organisms.
On this occasion however, her total white cell count was 29.9 x [10.sup.9]/L, consisting of a neutrophil count of 23.92 x [10.sup.9]/L with concurrent basophilia
and eosinophilia (Table 1).
Particularly important is the detection of variations in cell shape and of red cell inclusions, such as Howell-Jolly bodies (nuclear fragments), Pappenheimer bodies (hemosiderin-containing granules) and basophilic stippling or punctate basophilia
According to the histological analysis, hepatocytes were rounded and arranged in a slightly cordonal organization around sinusoidal capillaries, and showed a core with high basophilia
and vacuolated cytoplasm.
Some cases of MDS show basophilia
or eosinophilia in the bone marrow, which indicates a poor prognosis [2, 3].
These bodies had variable sizes (mostly between 5 and 30 micrometers) and presented varying degrees of basophilia
on Hematoxylin-Eosin (HE) staining (blue/gray).