benzidine


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ben·zi·dine

 (bĕn′zĭ-dēn′)
n.
A carcinogenic yellowish, white, or reddish-gray crystalline powder, C12H12 N2, that is a derivative of biphenyl, is used in dyes, and is used to detect blood stains and cyanide.

benzidine

(ˈbɛnzɪˌdiːn; -dɪn)
n
(Elements & Compounds) a grey or reddish poisonous crystalline powder that is used mainly in the manufacture of dyes, esp Congo red. Formula: NH2(C6H4)2NH2

ben•zi•dine

(ˈbɛn zɪˌdin, -dɪn)

n.
a crystalline base, C12H12N2, used in the synthesis of azo dyes, esp. Congo red.
[1875–80; benz- + -idine]
References in periodicals archive ?
A related study in the same cohort examined the role of modeled levels of 24 mammary gland carcinogens (MGCs) at the residence and found associations between propylene oxide and vinyl chloride and overall breast cancer risk, as well as associations for acylamide, benzidine, carbon tetrachloride, ethylidene dichloride, and vinyl chloride with ER + /PR + breast cancer and for benzene with ER--/PR--breast cancer (Garcia et al.
The substrate solution, tetramethyl benzidine (100 [micro]l) was immediately added into each well followed by incubation at room temperature away from light for 20 minutes.
Sections were visualized with 3,3'-diamino benzidine (DAB; Dako; Glostrup, Denmark).
Results and Discussion Synthesis of Dyes 6a-j Synthesis of Congo red dye and its derivatives (6a-j) was achieved in excellent yields, according to the synthetic strategy outlined in scheme 1 starting from benzidine (1).
A total of 100 [micro]l of Tetra Methyl Benzidine (TMB) chromogenic substrate was then dispensed in to each well and the plates were then incubated for 30 minutes at room temperature.
Next, the enzyme substrate (3,3',5,5'-tetramethyl benzidine peroxidase substrate and peroxidase solution B) was added, and the samples were incubated for 15 min (IgM) or 30 min (IgG).
Each sample was analyzed in duplicate using, peroxidase as the enzymatic tracer, a polyclonal antibody (L2) and tetramethyl benzidine as color reagent (L2 antibodies have a six-to eightfold higher affinity for ecdysone than for 20E).
Those most commonly used in clinical biochemistry were aromatic amines such as benzidine and ortho-tolodine.
Excess HRP-conjugate is washed off and solution of tetra methyl benzidine (TMP) reagent was added.
I noticed that one of the starting materials for the API resembled benzidine (4,4'-diaminobiphenyl), a known carcinogen.