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Related to beta-lactam: beta-lactamase, Beta-lactam Ring


 (bā′tə-lăk′təm, bē′-)
1. A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
2. A beta-lactam antibiotic.

[beta, second (in the series of lactam rings, the first being the simplest) + lactam.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Hahn and colleagues recruited 20 patients between 1 to 21 years of age who were treated for APEs with beta-lactam antibiotics at Children's National.
Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery.
Summary: New Delhi [India], Dec 17 (NewsVoir): Effective December 10, 2018 Centrient Pharmaceuticals is the new name for DSM Sinochem Pharmaceuticals, the leading manufacturer of beta-lactam antibiotics and a provider of next-generation statins and anti-fungals.
Synthetic Biologics, in consultation with the FDA, has confirmed the key elements of the Phase 3 clinical program to support a marketing application for ribaxamase, the company's first-in-class oral enzyme designed to degrade certain intravenous beta-lactam antibiotics within the gastrointestinal tract to prevent microbiome damage, Clostridium difficile infection, overgrowth of pathogenic organisms and the emergence of antimicrobial resistance.
The acquisition will help us leverage our expertise in beta lactam manufacturing segment." (Beta lactam is a class of broad-spectrum antibiotics, consisting of all antibiotic agents that contain a beta-lactam ring in their molecular structures.)
QJRZ00000000), showed resistance to several beta-lactam and non-beta-lactam antibiotics, including colistin.
SYN-004 (ribaxamase) is designed to protect the gut microbiome from the effects of certain commonly used intravenous beta-lactam antibiotics for the prevention of C.
"Double coverage" for Pseudomonas infection usually includes the addition of an antipseudomonal fluoroquinolone or aminoglycoside to an antipseudomonal beta-lactam.
ATLANTA -- With the help of a pharmacist and the electronic health records system, Rochester (N.Y.) General Hospital ruled out penicillin allergies in 47 of 50 adult inpatients, and successfully transitioned them from second-line antibiotics to less expensive and more effective beta-lactam options.
A chemically tweaked version of one of these molecules made 82 percent of tested MRSA strains vulnerable to a beta-lactam antibiotic.
Almost all patients with positive antibodies to streptococci responded to beta-lactam antibiotics (97%).
Austin, TX, August 27, 2015 --( Bioo Scientific's MaxSignal[R] Beta-Lactam ELISA Test Kit has been validated for the screening of a wide range of beta-lactam antibiotics including ampicillin, penicillin G, amoxicillin, azlocillin, piperacillin, nafcillin, cloxacillin, oxacillin, cefoperazone, ceftiofur and other beta-lactams in a number of food matrices.

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