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The degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.

bi′o·a·vail′a·ble (-lə-bəl) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Medicine) the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous. Also called: systemic availability
ˌbioaˈvailable adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti)

the extent to which a substance can be used by the body.
bi`o•a•vail′a•ble, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
The "2020 Global Drug Bioavailability Enhancement Summit" conference has been added to's offering.
Curcumin supplement manufacturers have also been working on ways to increase bioavailability, and have tried formulations that use nanoparticles, liposomes, micelles, and phospholipid complexes.
Juniper's nearly 150 employees have scientific expertise in formulation development, and supply, and will augment Catalent's current portfolio of solid-state screening, preformulation, formulation, analytical, and bioavailability enhancement solutions, including development of spray-dried dispersions, with integrated development, analytical, and clinical manufacturing co-located in its Nottingham facility.
One theory is the simultaneous consumption of natural compounds that increase bioavailability. Black pepper, for example, has been shown to increase curcumin absorption, and the natural oils within turmeric may also improve circulatory levels of curcumin.
A subcategory of absorption, bioavailability represents the rate at and extent to which a substance reaches the systemic circulation in its unchanged form, thus becoming available at the target site (2-3).
"We will be looking at the bioavailability of the plasma processed protein and it will be a great complement to our first investigation."
In this article, we examined the Brazil's current regulation for prescription drug substitutability in light of the concepts of drug bioavailability, relative bioavailability and bioequivalence.
"We chose to measure bioavailability using area under the plasma concentration curve (AUC) because it accurately represents the total amount of unchanged active compounds that reach systemic circulation.
However, information on bioavailability of P in pea for broiler chickens is scarce.
Based on the results, the use of nano-encapsulated form of chyrsin results in effectiveness of the drug at low concentrations and improvement in the drug delivery in anticancer drugs with low bioavailability. Normal numerical bioavailability equals to a percentage or a part of a drug dosage that reaches to the blood cycle in an active manner.
Delivery systems consisting of lipid droplets encapsulated by nano-laminated biopolymer coatings have potential, but there is some concern about the bioavailability of the encapsulated lipids.