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The degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.

bi′o·a·vail′a·ble (-lə-bəl) adj.


(Medicine) the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous. Also called: systemic availability
ˌbioaˈvailable adj


(ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti)

the extent to which a substance can be used by the body.
bi`o•a•vail′a•ble, adj.
References in periodicals archive ?
The researchers acknowledge that smaller particles tend to penetrate better than larger particles and possibly are more bioavailable, due to their higher surface-to-volume ratio.
This could be a very important discovery because there's only a very small amount of soluble iron in the ocean and if plankton use the iron nanoparticles formed in clouds then the whole flux of bioavailable iron to the oceans needs to be revised," said Dr Zongbo Shi, lead author of the research from the School of Earth and Environment at the University of Leeds.
Recaldent, known for its ability to strengthen, remineralize and protect tooth enamel, remains bioavailable to remineralize teeth for up to three hours after chewing the new gum.
Investigators at the universities of Parma and Naples found that cooking often enhances the nutrition of vegetables because it softens them up, making their nutrients more bioavailable than in raw vegetables.
Named "Herald," it's the first commercial-quality barley that provides a greater proportion of its phosphorus in a bioavailable form that can be more readily absorbed and used by fish and nonruminant livestock, such as pigs.
Unlike the platinum drugs currently on the market, all of which require intravenous administration, satraplatin is an orally bioavailable compound and is given as capsules that patients can take at home.
The new products include GADOMAG+ (a citrate based magnesium supplement for food and beverage fortification), GADOCAL+ (a soluble calcium source) and GADOZINC+ (a bioavailable zinc source).
In this study, the osteoporotic and the osteopenic subjects regarding the levels of total, free and bioavailable sex steroids, SHBG and bone turnover markers were not different from the subjects with normal BMD.
MINTREX chelated trace minerals are highly bioavailable to the animal.
The beverage would also deliver higher concentrations of lutein in a more bioavailable matrix than do many common supplements.
To facilitate public access to more natural, powerful, effective and bioavailable formulations of hydroxytyrosol, Creagri, Inc.