biological marker


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Related to biological marker: CD11c

biological marker

n
1. (Medicine) a substance, physiological characteristic, gene, etc that indicates, or may indicate, the presence of disease, a physiological abnormality or a psychological condition. Also called: biomarker
2. (Psychology) a substance, physiological characteristic, gene, etc that indicates, or may indicate, the presence of disease, a physiological abnormality or a psychological condition. Also called: biomarker
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If the findings are replicated, a low cholesterol level might serve as an inexpensive and readily available biological marker of suicide risk in men [with psychiatric disorders]," conclude psychiatrist Julia A.
Washington, Jan 21 (ANI): A biological marker in the brains of those exhibiting post-traumatic stress disorder (PTSD) has been identified by researchers.
Two areas stand out: The left prefrontal cortex mallunctions only during bouts of depression, whereas the amygdala - a small, inner-brain structure thought to regulate emotional reactions -- operates abnormally both during and between depressive episodes, apparently serving as a biological marker of susceptibility to severe depression.
The A3AR was found during the Phase IIa study to serve as a biological marker to predict patient response to the drug.
Conceptually, a preplacement examination using a liver function assay resulted in the identification of a biological marker that the employer interpreted to suggest a heightened susceptibility to disability from workplace exposure.
Typically, exposures to single chemicals are measured because a biological marker is available, and individual differences in metabolism of specific chemicals may mean that a biomarker of a specific chemical may be a very poor marker of exposure to other chemicals in the mixture, which may be more etiologically relevant (16).
The average age at which the first Alzheimer's symptoms appeared for relatives of patients with increased platelet-membrane fluidity was more than five years younger than for relatives of patients without the potential biological marker.
Because [is greater than] 95% of lead in adults is stored in the skeleton (21,22), where lead has a half-life of years to decades, bone lead is superior to blood lead as a biological marker of cumulative lead exposure.
If further studies confirm the membrane aberration as a specific biological marker for Alzheimer's, laboratory techniques to measure membrane rigidity may be incorporated into diagnostic strategies, say the scientists.
Thirty-one (89%) patients had a significant tumor response, as measured by a 50% or greater decrease in the serum M-protein, a standard biological marker for multiple myeloma.

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