Aljoscha Koenneke, PhD Pharmacist, Institute of Biopharmaceutics
and Pharmaceutical Technology, Saarland University
, enduring and exhaustive exercise, metabolomics, pharmacokinetics
"Targeted delivery of p-coumaric acid encapsulated mannosylated liposomes to the synovial macrophages inhibits osteoclast formation and bone resorption in the rheumatoid arthritis animal model." European Journal of Pharmaceutics and Biopharmaceutics
It involves knowledge from nanobiotechnology, biotechnology and biopharmaceutics
. The different products so delivered are termed nanobiopharmaceuticals.
As usual for this congress, the spectrum of topics was very broad and ranged from "3D Models & Multi-Organ-Chips (MOCs), Human-Organ-Chips (HOCs)" to topics directly relevant for consumers such as "Advanced Safety Testing of Cosmetics and Consumer Products", "Alternatives to Animal Testing in Food Safety" and "Nutrition and Efficacy" as well as to the topics "Biological Barriers", "Disease Models Using Human Cells, Tissues and Organs", "Efficacy and Safety Testing of Drugs, Medical Devices & Biopharmaceutics
", "In Silico Models: Toxicology & Efficacy of Drugs, Chemicals & Cosmetics", "In vitro Techniques for CNS Toxicity and Disease Studies" and "Vaccines & The 3Rs: New Methods and Developments (e.g., Batch Release Testing)".
The present work is part of the evaluation pharmacokinetic herbs-drug interactions study of piroxicam in Biopharmaceutics
Laboratory, Department of Pharmacy, University of Peshawar, Pakistan.
Spireas is the inventor and author of more than 80 international and domestic patents and 200 scientific papers, books and other publications in the fields of industrial pharmacy, biopharmaceutics
, pharmacokinetics, pharmaceutical technology and analytical chemistry.
However, the US FDA's implementation of the Biopharmaceutics
Classification System (BCS), allowing biowaivers of in vivo bioequivalence (BE) studies for BCS Class 1 and BCS Class 3 APIs, has resulted in improved access to good-quality, affordable generic drugs.
One strategy is outsourcing manufacturing of relatively old biopharmaceutics
such as insulin, interferon, interleukin, or growth hormones, to a CMO and utilize their own facilities for newer and more valuable biological pipeline.
Fang, "Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: hysicochemical characterization and pharmacokinetics," European Journal of Pharmaceutics and Biopharmaceutics
Alvariza et al., "Skin reactions associated to phenytoin administration: multifactorial cause," Clinical Pharmacology & Biopharmaceutics
Sutariya, "Reversed chitosan-alginate polyelectrolyte complex for stability improvement of alpha-amylase: optimization and physicochemical characterization," European Journal of Pharmaceutics and Biopharmaceutics