biosafety level


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Noun1.biosafety level - the level of safety from exposure to infectious agentsbiosafety level - the level of safety from exposure to infectious agents; depends on work practices and safety equipment and facilities
tier, grade, level - a relative position or degree of value in a graded group; "lumber of the highest grade"
biosafety level 1 - exposure only to infectious agents that do not ordinarily cause human disease
biosafety level 2 - exposure to infectious agents that can cause disease in humans but whose potential for transmission is limited
biosafety level 3 - exposure to infectious agents that can be transmitted by the respiratory route and which can cause serious infection
biosafety level 4 - exposure to exotic infectious agents that pose a high risk of life-threatening disease and can be transmitted as an aerosol and for which there is no vaccine or therapy
References in periodicals archive ?
BMBL section III: laboratory biosafety level criteria.
Antimicrobial PEP is not needed for vaccinated persons working in Biosafety Level 3 laboratories under recommended conditions (10) nor for vaccinated persons (six vaccinations according to the current label) wearing appropriate personal protective equipment (PPE) while working in contaminated environments in which inhalational exposure to B.
meningitidis is classified as a biosafety level 2 organism (4).
Regional state public health laboratories and reference laboratories with biosafety level 3 facilities should have virus isolation and identification capabilities.
On May 9, blood samples from 14 acutely ill persons arrived at CDC and were processed in the biosafety level 4 laboratory; analyses included testing for Ebola antigen and Ebola antibody by enzyme-linked immunosorbent assay, and reverse transcription-polymerase chain reaction (RT-PCR) for viral RNA.
BAV is now classified as a biosafety level 3 arboviral agent (www.cdc.gov/od/ohs/biosfty/bmb14/bmb14s74.htm).
The new $63-million, 195,000-square-foot facility will be one of five labs in the United States equipped with Biosafety Level 4 lab space specifically designed to meet worldwide standards for safely handling the most dangerous pathogens.
On the other hand, converting a large and busy clinical microbiology laboratory into a biosafety level III facility, where all specimens are handled in biologic safety cabinets (32), is both impractical and unnecessary, especially in laboratories in areas where the disease is not endemic.
The Bethesda laboratory will be a BioSafety Level 3 facility, which requires precautions such as containment of airflow.
However, studies of neutralizing antibody responses during natural infection have been limited (8,9), partially because neutralization assays must be performed at biosafety level 3 or higher.