bleomycin


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Related to bleomycin: cisplatin, doxorubicin

ble·o·my·cin

 (blē′ə-mī′sĭn)
n.
Any of a class of antibiotics isolated from the bacterium Streptomyces verticillus, used usually in sulfate form in combination with other drugs to treat certain kinds of cancer.

[Alteration of phleomycin, a related antibiotic : phleo-, of unknown meaning + -mycin.]

bleomycin

(ˌbliːəʊˈmaɪsɪn)
n
(Pharmacology) a glycopeptide antibiotic drug used in the treatment of cancer and Hodgkin's Disease
[C20: from bleo- unknown + -mycin]
Translations
bléomycine

bleomycin

n bleomicina
References in periodicals archive ?
"After the first treatment, the consultants could not believe how well I was taking to the bleomycin.
This study was designed primarily to assess the evidence for the efficacy of intralesional bleomycin in treating plantar warts and also to see the outcome in terms of duration of treatment in each case and identify side effects, if any, due to this drug.
Treatment of verruca vulgaris in both external auditory canals using bleomycin injections.
Adjuvant therapy of ovarian germ cell tumors with cisplatin, etoposide, and bleomycin: a trial of the Gynecologic Oncology Group.
Based on molecular data, the authors highlighted the optimal use of the bleomycin model and suggested this gene set in IPF clinical practice for diagnostic and prognostic purposes.
Randomized trial of bleomycin, etoposide, andcisplatin compared with bleomycin, etoposide, and carboplatin in good-prognosis metastatic nonseminomatous germ cell cancer: A multi-institutional Medical Research Council/European Organization for Research and Treatment of Cancer Trial.
For the bleomycin mouse model, 2 U/kg bleomycin (Nippon Kayaku Co Ltd., Tokyo, Japan) in 20-25 [micro]l phosphate-buffered saline (PBS) was administrated intratracheally using a 1 ml syringe with a 25 G needle inserted between the cartilaginous rings of the trachea.
After receiving three cycles of chemotherapy in the form of bleomycin, etoposide and cisplatin, she presented with recurrent pelvic mass on right side.
This is particularly applicable to patients > 50 years old or those with pulmonary compromise at diagnosis, groups with increased susceptibility to bleomycin lung toxicity in whom bleomycin is often avoided.
The BLM group mice were intratracheally injected with bleomycin sulfate (5 mg/kg mouse in 50 [micro]l saline) for 7 days to induce mice with pulmonary fibrosis.
We have investigated whether human ERCs (which exhibit immunomodulatory properties) have therapeutic effects on inhibiting pulmonary fibrosis in a mouse model and found that the lung in the untreated group became inflamed and mauve and had fibrous deposition under macrography (Figure 1(a)), suggesting that bleomycin had induced severe pulmonary fibrosis.