ENPNewswire-August 13, 2019--MIT - Tissue model reveals role of blood-brain barrier
The major challenge to CNS drug delivery is the blood-brain barrier
(BBB), which limits the access of drugs to the brain substance.
Strategic Research Priority: Bioscience for Health Abstract Several foreign cell types have the intrinsic propensity to cross the mammalian blood-brain barrier
and establish themselves in the brain causing various types of disease.
NEW YORK, N.Y., June 6, 2019 -- In a new study, scientists have recreated a critical brain component, the blood-brain barrier
, that functioned as it would in the individual who provided the cells to make it.
The FUS technique temporarily opens the blood-brain barrier
in a specific part of the brain to allow drugs to reach just that part.
Israeli scientists at the Ben-Gurion University of the Negev have recently been successful in duplicating a blood-brain barrier
outside the patient's body using stem cells and microfluidic chips, producing a functioning copy of a patient's brain structure and thus advancing personalized medicine.
Per-Ola Freskgard to strengthen BioArctic's development of its technology platform to facilitate passage of antibodies and other biologics across the blood-brain barrier
[USA] Apr 22 (ANI): A recent study claims that obesity can break down the protective blood-brain barrier
, which can result in memory loss and learning issues, claim researchers.
10,183,078, relating to a novel approach of using HER3-targeted Eosomes as a shuttle system for transporting various classes of therapeutics across the blood-brain barrier
for treatment of brain disorders, including brain cancer.
15, systematically injecting a low dose of a protein called vascular endothelial growth factor temporarily increases the permeability of the blood-brain barrier
, a system that blocks about 98 percent of medicines from entering the brain.
This is known as the blood-brain barrier
. However, as we age, the blood vessels don't fit as tightly together, which may allow amyloid beta and tau to enter the brain.
Ischemic stroke is a leading cause of death and disability, and the ischemic brain remains a difficult to reach anatomical target because of the blood-brain barrier
which limits availability of systemically administered drugs.