The osteoinductive property of decalcified bone matrix
. An experimental study.
This platform technology is combined with DBX demineralized bone matrix
to promote bone growth in spinal fusion.
Aplication of demineralized human bone matrix
in the surgical dental fusion treatment.
Papers in the first section of the book discuss the basic biology of human growth and its relationship to cardiovascular and renal growth and disease, development of bone matrix
, and genetic aspects of disease in later life.
For example, bone matrix
proteins to regenerate bone growth have been demonstrated in the treatment of osteoporosis and spine degeneration.
The process of demineralization apparently releases bone morphogenetic proteins from the bone matrix
, allowing these potent factors to induce stromal cells in the adjacent tissue to differentiate along osteoblast lineage.
This tissue is later replaced by type I collagen (2), which makes up more than 90% of the mature bone matrix
. Human cartilage glycoprotein 39 (YKL-40), a recently described glycoprotein that belongs to the 18 glycosyl hydrolase family (3), was measured for the first time during fracture healing.
Tissue products used for transplantation typically include bone, demineralized bone matrix
, skin, and soft tissue (e.g., tendons) (1).
Cathepsin K is an enzyme required for hydrolysis of the bone matrix
, inhibiting the enzyme reduces bone resorption.
They speculated that the region of lower Pb concentration has lower blood flow in the Haversian canals and, consequently, less Pb available for uptake into bone matrix
during bone remodeling (Todd et al.
"The production of the bone matrix
is dependent on vitamin K," says Dawson-Hughes.
D is critical for calcium absorption, and magnesium is an important bone-building mineral that helps make up the bone matrix