Bowenoid papulosis is another HPV-associated disease affecting the squamous epithelium.
The histopathologic features of bowenoid papulosis overlap significantly with those of basaloid HSIL (Bowen disease).
High-risk HPV in bowenoid papulosis can be detected by in situ hybridization or PCR-DNA sequencing.
Amongst these are relatively rare entities such as bowenoid papulosis, epidermolytic acanthoma, and verruciform xanthoma, which are underrecognized by surgical pathologists.
(27) Bowenoid papulosis
, caused by human papilloma virus appears first during pregnancy or may get aggravated.
Location of the disease made us to think of condyloma acuminata and bowenoid papulosis
. But genital region was free of lesion.
Other clinical presentations of HPV include bowenoid papulosis
and epidermodysplasia verruciformis.
(57) Condyloma reactivity is similarly negative, sporadic (<5% isolated cells), or focal (<25%, small clusters), in comparison to the diffuse, full-thickness positivity seen in bowenoid papulosis
Human papillomavirus type-16-related DNA in genital Bowen's disease and in bowenoid papulosis
. Int J Cancer 1983; 32:563-5.
Friedrich suggested the term reversible vulva atypia, but in 1978, Wade, Kopf, and Ackerman coined the term Bowenoid papulosis because these lesions looked histologically like Bowen disease but were clinically different in both appearance and in natural history .
In 1994, Gross et al  demonstrated that typical condylomata acuminata and flat condyloma-like lesions were due to HPV-6 or --11, whereas papular and pigmented lesions with severe atypia, referred to as Bowenoid papulosis, were due to HPV-16.
In this classification, Bowenoid papulosis is considered as a separate lesion and is not included as a PeIN lesion.