Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.


 (brăd′ĭ-kī′nĭn, -kĭn′ĭn)
A biologically active polypeptide, consisting of nine amino acids, that forms from a blood plasma globulin and mediates the inflammatory response, increases vasodilation, and causes contraction of smooth muscle.

[brady- + Greek kīnein, to move; see keiə- in Indo-European roots + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌbrædɪˈkaɪnɪn; ˌbreɪdɪ-)
(Physiology) a peptide in blood plasma that dilates blood vessels and causes contraction of smooth muscles. Formula: C50H73N15O11
[C20: from brady- + Greek kin(ēsis) motion + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌbræd ɪˈkɪn ɪn, -ˈkaɪ nɪn)

a peptide hormone that dilates blood vessels and increases capillary permeability.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Thirdly, ACEI-induced angioedema, a reaction, in which the inhibition of the degradation of bradykinin is observed, resulting in angioedema, but not urticaria.
The first relates to the release of histamine and serotonin, the second (90-150 min) is mediated by the release of bradykinin (38), and finally in the third phase, the mediator is suspected to be prostaglandin (22).
Bradykinin is a peptide that causes blood vessels to dilate, reducing blood pressure; substance P, which is also a peptide, can act as a neurotransmitter.
Effects of intracoronary administration of bradykinin on the impulse activity of afferent sympathetic unmyelinated fiber with left ventricular endings in the cat.
Carrageenan induces inflammation through release of histamine, serotonin (early phase), prostaglandins and bradykinin (later phase) (Burch and DeHaas, 1990).
ACE inhibitors like lisinopril act by inhibiting ACE, decreases angiotensinogen II activity and increases the bradykinin and (met) enkaphalin.
Randomized placebo-controlled trial of the bradykinin B2 receptor antagonist icatibant for the treatment of acute attacks of hereditary angioedema: The FAST-3 trial.
Physical Activity reduces the action of angiotensin converting enzyme (ACE), which consequently decreases the action of Angiotensin II (vasoconstrictor) and increases the bioavailability of the enzyme bradykinin (vasodilator) (11).
Inflammation is initiated by Prostaglandins, bradykinin and histamine.
Bradykinin (BK) is a nine amino acid vasoactive peptide that is produced by the proteolytic action of kallikrein on the precursor kininogen (KNG).