bromocriptine


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Related to bromocriptine: Cabergoline

bro·mo·crip·tine

 (brō′mō-krĭp′tēn)
n.
An ergot alkaloid, C32H40BrN5O5, that is a dopamine antagonist and is used in its mesylate form to treat Parkinson's disease, acromegaly, and excessive prolactin secretion, and to reduce the size of certain pituitary tumors.

[bromo- + (ergo)cryptine, an ergot alkaloid (from German Ergokryptin : Ergo(t), ergot + Greek kruptos, hidden; see cryptic + -in, -in).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

bromocriptine

(ˌbrəʊməʊˈkrɪptiːn)
n
a dopamine agonist drug which blocks the release of prolactin from the pituitary gland, used in the treatment of Parkinson's disease
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Translations

bromocriptine

n bromocriptina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Recovery from postpartum cardiomyopathy in 2 patients by blocking prolactin release with bromocriptine. Journal of the American College of Cardiology 2007;50(24):2354-2355.
In agreement with the present findings and this tenet are the observations that timed bromocriptine therapy improved maximally insulin stimulated glucose disposal during a euglycemic-hyperinsulinemic clamp in severely insulin resistant T2DM subjects on oral antidiabetes agents [25].
Animal studies have found that selective D2 receptor agonist bromocriptine can reduce alcohol intake and acute ethanol tolerance in alcoholic rats.
Bromocriptine and cabergoline are effective in curing hyperPRL, but 12% of patients can not endure bromocriptine [6], and the expense of them is very expensive [7].
Treating early Parkinson's disease with dopamine agonists such as bromocriptine can improve symptoms (SOR: B, Cochrane reviews, RCTs with heterogeneity).
Side effects with these drugs are nausea, daytime sleepiness, headache and orthostasis, but they are safer than the ergot-derived dopamine agonists, such as bromocriptine and cabergoline.
Mr Cerrato: Can you briefly review the hypoglycemic medications currently available to physicians, and tell us specifically about the newest treatment option: bromocriptine quick release (QR)?
Bromocriptine was prescribed in 17 (17.5%) patients, of these 15 had Prolactinoma; 1 patient had Acromegaly and 1 had Empty sella with hyperprolactinemia.
Finally, bromocriptine inhibits serum prolactin and has been reported to provide 65% improvement in breast pain.
Of 172 patients with hyperprolactinemia (micro- and macroadenomas plus some patients with idiopathic hyperprolactinemia), 77.3% were treated with cabergoline and 13.4% with bromocriptine. The remaining 9.3% were switched from bromocriptine to cabergoline because of treatment failure.
Dopamine receptor agonists, such as cabergoline or bromocriptine, have been shown to suppress prolactin secretion.
Bromocriptine offers minimal response and surgical treatment has also been tried for these adenomas.