Mucus, neutrophils, eosinophils, and lymphoplasmacytic cells infiltrating the bronchiolar
wall were detected in the lumen (Figure 3).
Report for every sample should include the following: site (segment from which the sample comes), size (2 maximum diameters in perpendicular directions assessed at the microscope), "central sampling" (mainly bronchial with cartilage plates identified or bronchiolar
structures in greater than 40% of the surface of the sample), "peripheral sampling" (with or without visceral pleura, with alveoli present in at least 60% of the surface of the sample), and histologic pattern (respiratory bronchiolitis, desquamative interstitial pneumonia, NSIP, organizing pneumonia, UIP, capillaritis, among others).
wall is also seen (Red arrow) (H&E, 10x)
and alveolar epithelial cell degeneration and necrosis as well as desquamation were also observed.
The specific immunostainings were characterised by the presence of light to dark brown stained antigens demonstrated in: bronchial, bronchiolar
epithelial cells, macrophages, leukocytes, pneumocytes, giant cells and the desquamated bronchial and bronchiolar
These include spontaneous rupture of subpleural blebs, necrosis of implants on visceral pleura with resultant air leakage, prostaglandin-induced bronchiolar
constriction or bronchial obstruction by endometrial implants, resulting in alveolar rupture, and finally, leakage of air from the genital tract through congenital or acquired defects in the diaphragm.
It is a rare condition characterized by generalized proliferation of neuroendocrine cells confined to bronchial and bronchiolar
(A) Subpleural architectural distortion with fibrosis (star) and abnormal airspaces and bronchiolar
metaplasia (arrow) (100x magnification).
Multiple cells populations, including the bronchiolar
epithelium Clara cells/club cells, manage these inflammatory reaction.
In the lung, we observed IDV immunostaining in type I pneumocytes, macrophages, and bronchiolar
epithelial cells (Figure 3).
To elucidate the function of TAZ in NSIP by analyzing the differences in TAZ expression between the two types of NSIP, we compared TAZ expression levels in fibroblasts, bronchiolar
cells, and alveolar cells between the NSIP cellular and fibrotic groups.
walls with marked thickening contained moderate to heavy amounts of carbon and mineral dust, and wall thickening is associated with increase in collagen and interstitial inflammatory cells including dust-laden macrophages.