bupropion


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Related to bupropion: Wellbutrin, bupropion hydrochloride

bu·pro·pi·on

 (byo͞o-prō′pē-ŏn′)
n.
A drug, C13H18ClNO, used in its hydrochloride form for the treatment of depression and as an aid in smoking cessation. It is a weak inhibitor of norepinephrine and dopamine reuptake in the central nervous system.

[bu(tyl) + propi(ophen)on(e), a ketone (propio(nic acid) + phen(yl) + -one).]

bupropion

(bjuːˈprəʊpɪɒn)
n
an antidepressant drug used to help people stop smoking
Translations

bupropion

n bupropión m
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References in periodicals archive ?
Adolescents who attempt self-harm using bupropion are at a significantly higher risk of serious morbidity and poor outcomes, compared with those who attempt self-harm with selective serotonin reuptake inhibitors (SSRIs), said Adam Overberg, PharmD, of the Indiana Poison Center in Indianapolis and associates.
The analysis showed that AXS-05 met the prespecified primary endpoint and significantly reduced daily smoking as compared to the active comparator bupropion. The trial was conducted at the Duke Center for Smoking Cessation under a research collaboration between Axsome and Duke University.
* Participants were randomly assigned to 1 of 3 groups: switching to bupropion (n = 511), augmenting with bupropion (n = 506), or augmenting with aripiprazole (n = 505).
* And finally, if the smoker is using a non-nicotine replacement prescription medicine containing bupropion hydrochloride or varenicline, stay alert to any serious mood or behavior changes or an intent to cause harm.
This agreement allows Orexigen to sell the world-wide rights to Contrave (naltrexone HCl / bupropion HCl extended release) /Mysimba (naltrexone HCl and bupropion HCl prolonged release) and certain other Orexigen assets for USD75m in cash.
Bupropion is a preferential norepinephrine and dopamine reuptake inhibitor [22].
The label for bupropion (Zyban) will still include a boxed warning, but language describing the potential for serious psychiatric adverse events will no longer appear within it.
Neuropsychiatric adverse events do not increase significantly in smokers treated with either varenicline or bupropion, a large cohort study shows.
Patients with major depressive disorder (MDD) who have previously failed one or two antidepressant treatments will be treated in an open-label fashion with bupropion during a 6-week lead-in period.
and Takeda Pharmaceuticals U.S.A., Inc., a wholly-owned subsidiary of Takeda Pharmaceutical Company Limited (TSE:4502) (collectively Takeda), today announced they have agreed to terminate the Amended and Restated Collaboration Agreement for CONTRAVE (naltrexone HCl / bupropion HCl), the market leading national branded prescription treatment option for certain overweight and obese adults for chronic weight management.
FDA-approved pharmacotherapies The only pharmacotherapies currently approved for use in the treatment of tobacco dependence in nonpregnant adults are nicotine replacement therapies (NRT: transdermal patches, gum, lozenges, nasal spray, or inhalers), bupropion SR, and varenicline.