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Weight loss, wasting of muscle, loss of appetite, and general debility that can occur during a chronic disease.

[Late Latin, from Greek kakhexiā : kako-, caco- + hexis, condition (from ekhein, to have; see segh- in Indo-European roots).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(kəˈkɛksɪə) or


(Pathology) a generally weakened condition of body or mind resulting from any debilitating chronic disease
[C16: from Late Latin from Greek kakhexia, from kakos bad + hexis condition, habit]
cachectic, cachectical, cachexic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(kəˈkɛk si ə)

also ca•chex•y


general ill health with emaciation, usu. occurring in association with a disease.
[1535–45; < Late Latin < Greek, =kak(ós) bad + héx(is) condition]
ca•chec′tic (-tɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

cachexia, cachexy

general physical or mental poor health; weakness or malnutrition.
See also: Health
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cachexia - any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease
debility, feebleness, frailness, frailty, infirmity, valetudinarianism - the state of being weak in health or body (especially from old age)
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. caquexia, condición grave que se caracteriza por pérdida excesiva de peso y debilidad general progresiva.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
At the time of presentation, he was in a chronic cachexic state, with the following laboratory values: sodium, 122 mEq/L; potassium, 3.3 mEq/L; chloride, 82 mEq/L; glucose, 88 mg/dL; serum albumin, 2.9 g/dL; total cholesterol, 86 mg/dL; triglyceride, 23 mg/dL.
On physical examination, it was found that he was cachexic. His weight was in the 3rd percentile.
It appears feasible from these findings that glucose-depleted, low ATP, and [NAD.sup.+]-rich states (in cachexic patient with advanced cancer) may drive the M2-like activation of macrophages, while the macrophage population still retains its phagocytic activity in maintaining biosynthesis with molecules acquired from their microenvironment [32].
Thus our study does not give any information about cachexic and morbidly obese patients.
The increasing prevalence of sarcopenic and cachexic muscle degeneration necessitates the establishment of a gold standard for quantitative myological assessment.
The initial head injury may be a consequence of the underlying cachexic malnourished status, which may later become a deteriorating factor in the terminal status.
On examination he was cachexic and pale with no other significant clinical findings.
* Cachexic patient/medical comorbidities resulting in poor healing at fracture site.