cadherin


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cad·her·in

 (kăd-hîr′ĭn)
n.
Any of a group of proteins that span the plasma membrane of eukaryotic cells and, in the presence of calcium, bind to identical proteins in adjacent cells, thus linking cells together in tissues.

[Blend of ca(lcium) + adher(e) + -in.]
References in periodicals archive ?
Combining cadherin expression with molecular markers discriminates invasiveness in growth hormone and prolactin pituitary adenomas.
The topics include the integration of cadherin adhesion and cytoskeleton at adherens junction, making connections: guidance cues and receptors at non-neural cell-cell-junctions, tuning collective cell migration by cell-cell junction regulation, beyond cell-cell adhesion: sensational cadherins for hearing and balance, and the loss of E-cadherin-dependent cell-cell adhesion and the development and progression of cancer.
Numerous isoforms of cadherin have been identified in a tissue-specific manner and shown to regulate morphogenesis through homophilic binding (Nose et al.
Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling.
The loss of E- Cadherin, alpha- and beta- catenin expression is associated with metastasis and poor prognosis in invasive breast cancer.
In first, to induce toxicity the sequential binding takes place with multiple receptors, while according to the second, binding to the cadherin stimulates an intracellular reactions cascade leading to the toxicity in cell.
The GLE suppressed the TGF-[beta]1 -induced morphological changes and the changes in cadherin expression, and also inhibited the formation of F-actin stress fibers, which are a hallmark of EMT.
E-cadherin is a member of the cadherin superfamily, serving as the main epithelial intercellular adhesion molecule.
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt.
Among them is the Human Epithelial Cadherin (E-cadherin), a calcium-dependent trans membrane glycoprotein directly involved in the process of cell adhesion.
Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms.