Release date- 07082019 - Copenhagen - MC2 Therapeutics A/S, a late clinical-stage pharmaceutical company focused on topical therapies for chronic inflammatory conditions, today announced the completion of enrollment for its EU Phase 3 study assessing the safety and efficacy of MC2-01 PAD Cream (calcipotriene and betamethasone dipropionate, w/w 0.005%/0.064%) in adult patients with plaque psoriasis compared to Daivobet gel (marketed in the US as Taclonex Topical Suspension).
- The US Food and Drug Administration has expanded the approved indication for Enstilar (calcipotriene and betamethasone dipropionate) Foam, 0.005%/0.064%, for the topical treatment of plaque psoriasis to include patients age 12 and older, US-based medical dermatology company Leo Pharma Inc., a wholly owned subsidiary of Denmark-based Leo Pharma A/S, said.
Yet another example of changing the vehicle to improve efficacy can be seen with the fixed-dose combination of calcipotriene and betamethasone dipropionate.
Pharmaceutical company Mayne Pharma Group Limited (ASX:MYX) reported on Wednesday the receipt of approval from the US Food and Drug Administration (FDA) for SORILUX (calcipotriene) Foam, 0.005%, for treating plaque psoriasis of the scalp and body in patients aged 12 years and older.
In a randomised, double-blinded, controlled trial of Van der Vleuten CJ et al, [21] 71.2% of patients achieved "absent" or "very mild" disease with the two-compound scalp formulation, compared to 64% with betamethasone dipropionate and 36.8% with calcipotriene alone.
Combined topical calcipotriene ointment 0.005% and various systemic therapies in the treatment of plaque-type psoriasis vulgaris: review of the literature and results of a survey sent to 100 dermatologists.
Since our patient's underlying CML necessitated continued treatment with dasatinib and he declined procedural treatments, we treated his dyschromia topically with mometasone 0.1% and calcipotriene 0.005% creams.