In this study, we directlycharacterized, for the first time, free and glucuronidated THC and THCCOOH, 11-OH-THC, cannabidiol (CBD), and
cannabinol (CBN) in cannabis smokers after a single smoked cannabis cigarette.
The objectives of this research were to examine THC, THCCOOH, cannabidiol (CBD), and
cannabinol (CBN) OF concentrations in chronic, daily cannabis smokers during sustained abstinence, and to establish OF cutoff concentrations for maximizing the diagnostic sensitivity of OF test results, reduce the potential of passive smoke exposure, and account for residual cannabinoid excretion in chronic, daily cannabis smokers.
Meconium samples were assayed with a validated 2-dimensional GC-MS analytical method for THC; 11-hydroxy-THC; 8[beta],11-dihydroxy-THC; 11-nor-9-carboxy-THC (THCCOOH); and
cannabinol (21).
There are few data on the OF disposition of additional cannabinoids found in the cannabis plant, cannabidiol (CBD) and
cannabinol (CBN), (10).
A specialized extraction process is used to yield highly concentrated CBD oil or pure cannabidiol that also contains other nutritious material such as omega-3 fatty acids, terpenes, vitamins, chlorophyll, amino acids, and other phytocannabinoids like cannabichromene (CBD), cannabigerol (CBG),
cannabinol (CBN) and cannabidivarian (CBCV).
However, another cannabis compound --
cannabinol (CBN) -- did.
The cannabinoids detected on the wooden burners were mainly
cannabinol (CBN), which is what the main psychoactive component of cannabis, tetrahydrocannabinol (THC), decomposes into when exposed to air.
In 2007, Wilkinson and Williamson used a keratinocyte proliferation assay to study the phytocannabinoids delta (9)-tetrahydrocannabinol (THC), CBD, CBG, and
cannabinol (CNB) to assess their capacity to halt the growth of a hyper-proliferating human keratinocyte cell line with an eye toward potential use in treating psoriasis.
These include CBD and
cannabinol (CBN) and THC-glucuronide, respectively, which are detectable up to four to five hours.
Made from a custom, proprietary blend of essential oils and full-spectrum CBD--which includes additional beneficial compounds from the hemp plant, including CBN (
cannabinol), CBC (cannabichromene) and CBG (cannabigerol)--versus other products that contain just the isolated CBD compound, the New York-based retailer's hemp-extract products are non-GMO, pesticide-free and made from hand-picked hemp grown on sustainable farms in the U.S.