capsid


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

cap·sid

 (kăp′sĭd)
n.
The protein coat that constitutes the shell of a virus particle.

[From Latin capsa, box.]

capsid

(ˈkæpsɪd)
n
(Animals) any heteropterous bug of the family Miridae (formerly Capsidae), most of which feed on plant tissues, causing damage to crops
[C19: from New Latin Capsus (genus)]

capsid

(ˈkæpsɪd)
n
(Biochemistry) the outer protein coat of a mature virus
[C20: from French capside, from Latin capsa box]

cap•sid

(ˈkæp sɪd)

n.
the coiled or polyhedral structure, composed of proteins, that encloses the nucleic acid of a virus. Also called protein coat.
[1960–65; < French capside= Latin caps(a) case2 + -ide -id1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.capsid - a variety of leaf bugcapsid - a variety of leaf bug    
leaf bug, plant bug - small bright-colored insect that feeds on plant juices
four-lined leaf bug, four-lined plant bug, Poecilocapsus lineatus - yellow or orange leaf bug with four black stripes down the back; widespread in central and eastern North America
lygus bug - vector of viral plant diseases
2.capsid - the outer covering of protein surrounding the nucleic acid of a virus
virion - (virology) a complete viral particle; nucleic acid and capsid (and a lipid envelope in some viruses)
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
References in periodicals archive ?
The poster describes the results of an AAV gene therapy construct selection study conducted in a well-characterized mouse model of Pompe disease that evaluated both AAV8 and AAV9 capsid serotypes, paired with novel promoter elements designed to target GAA expression in a range of tissues, including skeletal and cardiac muscle, the nervous system and the liver.
The present results and those of another recent study utilizing a different AAV9 variant and transgene indicate that systemic and sensory neuron toxicity may be general properties of intravenous delivery of AAV vectors at high doses irrespective of the capsid serotype or transgene.
An accompanying paper in the same issue of Cell shows that a version of Arc found in flies also looks and acts like a viral capsid.
It is a member of the Parvoviridae family, and it's tiny, with a roughly 18 nm diameter, unenveloped icosahedral protein capsid carrying ~4700 bases of DNA.
We have to have a sense of these short-lived molecular fluctuations and processes - of protein cleavage and capsid generation.
Two recombinant proteins selected in non-structural area of ns3, ns4 and structural region (capsid ) of hcv and a monoclonal antibody against hepatitis ~c~ capsid ( liquid stable & ready to use ) 96 tests / pack
All these strains clustered in the same branch of the phylogenetic tree, with >95% amino acid sequence similarity in the viral capsid protein (online Technical Appendix Figure 2) and, therefore, should be considered 1 genotype species (9).
From there, the capsid disassembles through a process called "uncoating," which is crucial to the synthesis of viral DNA from its RNA genome and the hijacking of the cell's functions.
The viral DNA is contained within an icosahedral capsid that measures 45 nm-55 nm.
Although new drugs to prevent cccDNA formation and HBV life cycle events such as capsid assembly and HBeAg expression may further improve outcomes, they still may not be curative without better host defenses.
According to the company, SPK-9001 is a novel bio-engineered adeno-associated virus (AAV) capsid expressing a codon-optimized, high-activity human factor IX variant enabling endogenous production of factor IX.
The transmission electron microscopy of a crust showed multiple typical orf viral particles, which were enveloped with a brick-shaped morphology and consisted of a central DNA-containing core surrounded by a bilayered capsid [Figure 1]c-g.