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An ACE inhibitor drug, C9H15NO3S, used in the treatment of hypertension, congestive heart failure, and other cardiovascular disorders.

[(mer)capt(an) + -pr- (pr(opane) or pr(oline)) + alteration of -yl.]


(Pharmacology) an ACE inhibitor used to treat high blood pressure and congestive heart failure


(ˈkæp tə prɪl)

a white, crystalline powder, C9H15NO3S, used as an antihypertensive.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.captopril - a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
ACE inhibitor, angiotensin-converting enzyme inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure


n captopril m
References in periodicals archive ?
Captopril, an ACE inhibitor, has been demonstrated to exhibit protective effect on diabetic (5) and non-diabetic (6) renal injury.
Captopril (CAP), an inhibitor of the angiotensin-converting enzyme, is commonly used in the treatment of hypertension and most forms of heart failure.
O uso do captopril em urgencias hipertensivas tem se mostrado eficaz na reducao dos niveis pressoricos com boa tolerancia pelo paciente.
Antihypertensive medicines dispensed for free during SNP were: (i) beta-blocking agents: atenolol 25 mg and propranolol hydrochloride 40 mg; (ii) diuretics: hydrochlorothiazide 25 mg; and (iii) agents acting on the renin-angiotensin system inhibitors (Class C09 on European Pharmaceutical Marketing Research Association (EphMRA) Anatomical Classification) including (a) the angiotensin-converting-enzyme (ACE) inhibitors captopril 25 mg and enalapril maleate 10 mg; and (b) the angiotensin II antagonist or angiotensin receptor blocker (ARB) losartan potassium 50 mg (10).
Animals were randomly divided into 3 groups of 8 animals; control, Goldblatt 2K1C hypertensive rats and Goldblatt 2K1C hypertensive rats received 5 mg/kg captopril.
In this study, SHR was applied to observe characteristics and mechanism of the antihypertensive effect of QGQS granule on hypertension related metabolic syndrome, SHR was administrated with QGQS granule and captopril for 4 weeks, and the rat's blood pressure was compared among model group, control group, captopril group, and QGQS group firstly.
Captopril (98% purity) was purchased from Sigma-Aldrich (St.
TEHRAN (FNA)- Captopril is an edible drug that plays an essential role in the treatment of heart attack, heart malfunction and high blood pressure and persistent consumption of this drug results in side effects.
Moreover, captopril for hypertension was given to two IAS patients.
AAC rats were randomly divided into five groups: model control group, three angoroside C treated groups (7.5, 15 and 30 mg x [kg.sup.-1]) and captopril treated group (40 mg x [kg.sup.-1]).
Literature review shows multiple reports of DILI with captopril (2, 3), ramipril (4), fosinopril (5, 6) and enalapril.