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Any of several semisynthetic or synthetic beta-lactam antibiotics that are used chiefly to treat serious infections caused by bacteria that are resistant to other antibiotics.

[carba-, alteration of carbon + penem, kind of beta-lactam with a double bond (alteration of penam, similar beta-lactam with a single bond, influenced by -ene).]
References in periodicals archive ?
Researchers are developing a promising alternative to antibiotic treatment for infections caused by Klebsiella pneumoniae bacteria resistant to carbapenem antibiotics.
During the last five decades health care facilities around the globe have experienced the emergence of microorganisms like Methicillin resistant staphylococcus aureus (MRSA), Vancomycin resistant enterococcus (VRE), Extended spectrum beta lactamases (ESBL), Carbapenem resistant Enterobacteriacae (CRE), Carbapenem resistant Acinetobacter baumanni (CRAB) and many more antibiotic resistant microorganisms that microbiologists and clinicians have to memorize the alpha-betical acronyms and abbreviations.
Carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) express plasmid-encoded carbapenemases, enzymes that inactivate carbapenem antibiotics.
Carbapenem activiti against Pseudomonas aeruginos a: Respective contributions of OprD and efflux systems.
In this issue Julie Creighton and Clare Tibbs evaluated and compared the recently released MAST indirect carbapenemase test (ICT) and a modified carbapenem inactivation method (mCIM) test to determine their ability to detect carbapenemase production, and to reliably 'rule out' a non-carbapenemase producer.
The screening for carbapenem resistance was performed by meropenem and imipenem discs, and minimum inhibitory concentrations.
They become resistant to the carbapenem antibiotics when they acquire a certain DNA molecule that is linked to a gene that produces carbapenemase, an enzyme that breaks down the antibiotics, rendering them ineffective.
The effect of different carbapenem antibiotics (ertapenem, imipenem/cilastatin, and meropenem) on serum valproic acid concentrations.
Carbapenem resistance can be ascribed to several enzymes encoded by resistance genes including the production of various carbapenemases: K.
The epidemic of CRE began in the early 2000s with an outbreak of carbapenem -resistant Klebsiella pneumoniae harboring K.
United States-based Pfizer's fixed-dose antibacterial combo, Zavicefta (ceftazidime-avibactam), has indicated a comparable cure rate in its phase three REPROVE study compared to carbapenem antibiotic therapy, it was reported yesterday.