However, to properly perform its inhibitory function, MGP must be activated by vitamin K2 in a carboxylation
These experiments demonstrated that XLR-11 undergoes phase I and II metabolism, producing more than 25 metabolites (including 7 major metabolites) resulting from hydroxylation, carboxylation
, hemiketal and hemiacetal formation, etc.
An alternative pathway in high-molecular phthalates is carboxylation
of the monoesters.
Role of the propeptide and gamma-glutamic acid domain of factor IX for in vitro carboxylation
by the vitamin K-dependent carboxylase.
Manganese has important role on activates several enzymes which involve to oxidation reactions, carboxylation
, carbohydrates metabolism, phosphorus reactions and citric acid cycle.
Metabolites resulted from hydroxylation (M6, M7, M8, M14, M17, M18, M20, M21) with subsequent ring closure (M23, M30), carboxylation
(M11, M13, M14, M18, M27), and oxidative defluorination (M10, M12, M15, M16, M19, M23, M24, M28, M29).
EP can react with ROS both via oxidative carboxylation
and via formation of hydroxylated adducts at the 3-carbon (46).
2] in locations of carboxylation
or possible metabolic limitations of the plant.
Warfarin is known to produce an anticoagulant effect by inhibiting the cyclic interconversion of vitamin K and its epoxide, which is needed for the carboxylation
of several blood coagulation proteins (Hirsh et al.
2] concentration and carboxylation
efficiency (CE), C[O.
Partitioning of transfer and carboxylation
components of intracellular resistance to photosynthetic C[O.
32] Other enzymes in the pathway such as acetyl-CoA carboxylase (ACC) which catalyzes the carboxylation
of acetyl-CoA to Malonyl-CoA, can serve as a target.