Supplementary, mast cells granules contain sulphated proteoglycans (heparin in connective tissue mast cells or chondroitin sulphate in mucosal mast cells), histamine, serine proteases (cathepsin G, granzyme B, carboxypeptidase
A3), Plasminogen activating factor, Platelet Activating Factor, eosinophils and neutrophils chemotactic factors, pglucuronidase, aryl-sulfatase, and hexosaminidase .
Cloning and functional expression as a captoprilinsensitive carboxypeptidase
. J Biol Chem.
Aspartic protease, [beta]-galactosidase, peroxidase and serine carboxypeptidase
were detected in three Ephedra species.
There are many different pancreatic enzymes that are secreted as a part of the pancreatic fluid including: amylase (carbohydrates), lipase (triglycerides), carboxypeptidase
(proteins), chymotrypsin (proteins), trypsin (proteins), phospholipase (fats), elastases (protein), nucleases (nucleic acids) , and various proteases (protein).
Also zinc is part of some enzymes structure, such as: Alkaline Phosphatase, phosphatides lipase, Carboxypeptidase
, RNA polymerase, Dehydrogenase and Aldolase (Pandy et al, 2002).
Zinc is present as a prosthetic group in a number of metalloenzymes for example, carbonic anhydrase, alkaline phosphatase, carboxypeptidase
, catalyzing various key biochemical reactions in human body.
The "go or grow" poten-tial of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase
E and mediated by metabolic stress.
Rani, "Influence of NaCl salinity on the behaviour of protease, aminopeptidase and carboxypeptidase
in rice seedlings in relation to salt tolerance," Australian Journal of Plant Physiology, vol.
E/NFalpha1: a new neurotrophic factor against oxidative stress-induced apoptotic cell death mediated by ERK and PI3-K/AKT pathways," PloS ONE, vol.
Soubrier, "PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase
1)," Nucleic Acids Research, vol.
These studies revealed overexpression of metabolically significant proteins like carboxypeptidase
, enolase, fructose-1, 6-bisphosphatase, Hsp70, and Hsp83 and downregulation of a kinetoplast membrane protein (KMP11) and calcineurin in R-strains [29-31].
With a New York University Cancer Institute colleague, the researchers reported that the mixture of free-floating blood proteins created by the enzyme carboxypeptidase
N accurately predicted the presence of early-stage breast cancer tissue in mice and in a small population of human patients.