cefotaxime


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cef·o·tax·ime

 (sĕf′ō-tăk′sēm′)
n.
A broad-spectrum cephalosporin antibiotic, C16H17N5O7S2, given intravenously in the form of its sodium salt.

[cef(a)- + perhaps t(hi)a(zole) + (o)xime.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cefotaxime - a parenteral cephalosporin (trade name Claforan) used for severe infections of the lungs or throat or ears or urinary tract
cephalosporin, Mefoxin - one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
cefatoximecefotaxima
cefotaxim
cefotaxima

cefotaxime

n cefotaxima
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
The study developed statistical methods to predict phenotypic resistance from resistance genes for various combinations of the four bacterial species and the antibiotics gentamicin, tobramycin, ciprofloxacin, levofloxacin, trimethoprim-sulfamethoxazole, ertapenem, imipenem, cefazolin, cefepime, cefotaxime, ceftazidime, ceftriaxone, ampicillin, piperacillin and aztreonam.
To compare the outcome in patients undergoing elective gynaecological surgeries receiving single dose cefazolin prophylaxis as against those receiving antibiotics postoperatively (Cefotaxime & Metronidazole) for 5-7 days.
coli isolates were found more sensitive to Amikacin 57 (76%) followed by Imipenem 50 (66.67%), Ofloxacin 48 (64%), Ciprofloxacin 44 (58.67%), Norfloxacin 42 (56%) and were 100% resistant to Penicillin, Ceftriaxone, Ceftazidime and Cefotaxime. The current study recorded the prevalence rate of UTI caused by E.
We report a case of a neonate with persistent positive blood cultures for HLAR Enterococcus faecalis treated successfully with a combination of ampicillin and cefotaxime. Informed consent was obtained from the patient's family for this case report.
The faecal specimens from healthy individuals, patients, sewage sludge, cattle, chickens and raw meat (n = 122) were processed for microbiological analysis using MacConkey agar supplemented with cefotaxime. The identification of organisms was confirmed by API 10S and antimicrobial resistance profile was recorded by Kirby-Bauer disc diffusion method.
The rooting frequency observed on Murashige and Skoog (MS) medium supplemented with 0.2 mg L-1 indole acetic acid and 400 mg L-1 cefotaxime was found to be 100.00%.
ESBLs producing E.coli and K.pneumoniae showed 100% resistance to amoxicillin-clavulanic acid, ceftazidime, ceftriaxone, cefotaxime and aztreonam.
E coli showed maximum sensitivity (Table 2) for Ciprofloxacin (81.81%) followed by Norfloxacin (77.27%), Amikacin (68.18%), Gentamicin (63.63%), Ceftriaxone (59.09%), Chloramphenicol (54.54%), Tobramycin (54.54%) but lesser to Cefotaxime, Kanamycin, Neomycin and Enrofloxacin.
The analysis of drug resistance pattern showed that, among gram-negative isolates, decreased sensitivity was observed to be against the commonly used antibiotics such as amikacin (15.70%), gentamicin (13.90%), ampicillin + sulbactam (8.97%), and cefotaxime (8.07%).
Since the first report from Spain in 2000 of strains producing CTX-M-9 (6), which confers resistance to cefotaxime, various CTX-M-type ESBLs have been identified in Salmonella Virchow.
KEY WORDS: Suppurative otitis media; Culture; Kirby-Bauer disc diffusion method; Pseudomonas aeruginosa; Staphylococcus aureus; Morganella morganii; Escherichia coli; Vancomycin; Ceftazidime; Cefotaxime.
Cefotaxime belongs to the third generation of Cephalosporin and we considered it as a drug model because of its wide-spectrum of antimicrobial activity and its excellent water solubility [36].