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A broad-spectrum cephalosporin antibiotic, C16H17N5O7S2, given intravenously in the form of its sodium salt.

[cef(a)- + perhaps t(hi)a(zole) + (o)xime.]
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Noun1.cefotaxime - a parenteral cephalosporin (trade name Claforan) used for severe infections of the lungs or throat or ears or urinary tract
cephalosporin, Mefoxin - one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity


n cefotaxima
References in periodicals archive ?
According to an NPPA notification, the prices of formulations, including Ciprofloxacin Hydrochloride, Cefotaxime, Paracetamol, Domperidone and Metformin+ Glimepiride, have
Cefotaxime belongs to the third generation of Cephalosporin and we considered it as a drug model because of its wide-spectrum of antimicrobial activity and its excellent water solubility [36].
Rapid identification of ESBL producers is possible by using the ESBL Nordmann/Dortet/Poirel (NDP) test (9), which is based on the biochemical detection of the hydrolysis of the b-lactam ring of cefotaxime (a broad-spectrum cephalosporin).
One vial was removed just before antibiotic susceptibility testing and 5 [micro]l of clavulunate solution was added to the cefotaxime (30 [micro]g) disc (Hi-Media, Mumbai).
Blood and urine cultures were obtained and empirical cefotaxime 200 mg/kg/day were initiated.
Extended-spectrumbeta-lactamase mediated resistance was assessed by disc diffusion method of four antibiotics ceftazidime, cefpirome, cefpodoxime and cefotaxime and corresponding disc containing ceftazidime/clavulanic acid, cefpirome/clavulanic acid, cefpodoxime/clavulanic acid and cefotaxime/clavulanic acid.
All strains were susceptible to ampicillin, cephalothin, cefotaxime, enrofloxacin, nalidixic acid, gentamicin, streptomycin, chloramphenicol, fosfomycin, tetracycline, nitrofurantoin, and trimethoprimsulfamethoxazole.
Intravenous cefotaxime is excreted via saliva, bile and mucus into throat and gut, and has been shown to eradicate carriage of 'normal' potential pathogens such as S pneumoniaa S.
Patients in the antibiotic group received 2 days of intravenous therapy consisting of cefotaxime 2 g twice daily and tinidazole 0.
Intraoperative and postoperative intravenous cefotaxime was given.
Amoxicillin, ampicillin, cefepime, cefotaxime, ceftriaxone, cefuroxime, ertapenem, imipenem, and meropenem must be tested by a MIC method.