The study developed statistical methods to predict phenotypic resistance from resistance genes for various combinations of the four bacterial species and the antibiotics gentamicin, tobramycin, ciprofloxacin, levofloxacin, trimethoprim-sulfamethoxazole, ertapenem, imipenem, cefazolin, cefepime, cefotaxime
, ceftazidime, ceftriaxone, ampicillin, piperacillin and aztreonam.
To compare the outcome in patients undergoing elective gynaecological surgeries receiving single dose cefazolin prophylaxis as against those receiving antibiotics postoperatively (Cefotaxime
& Metronidazole) for 5-7 days.
coli isolates were found more sensitive to Amikacin 57 (76%) followed by Imipenem 50 (66.67%), Ofloxacin 48 (64%), Ciprofloxacin 44 (58.67%), Norfloxacin 42 (56%) and were 100% resistant to Penicillin, Ceftriaxone, Ceftazidime and Cefotaxime
. The current study recorded the prevalence rate of UTI caused by E.
We report a case of a neonate with persistent positive blood cultures for HLAR Enterococcus faecalis treated successfully with a combination of ampicillin and cefotaxime
. Informed consent was obtained from the patient's family for this case report.
The faecal specimens from healthy individuals, patients, sewage sludge, cattle, chickens and raw meat (n = 122) were processed for microbiological analysis using MacConkey agar supplemented with cefotaxime
. The identification of organisms was confirmed by API 10S and antimicrobial resistance profile was recorded by Kirby-Bauer disc diffusion method.
The rooting frequency observed on Murashige and Skoog (MS) medium supplemented with 0.2 mg L-1 indole acetic acid and 400 mg L-1 cefotaxime
was found to be 100.00%.
ESBLs producing E.coli and K.pneumoniae showed 100% resistance to amoxicillin-clavulanic acid, ceftazidime, ceftriaxone, cefotaxime
E coli showed maximum sensitivity (Table 2) for Ciprofloxacin (81.81%) followed by Norfloxacin (77.27%), Amikacin (68.18%), Gentamicin (63.63%), Ceftriaxone (59.09%), Chloramphenicol (54.54%), Tobramycin (54.54%) but lesser to Cefotaxime
, Kanamycin, Neomycin and Enrofloxacin.
The analysis of drug resistance pattern showed that, among gram-negative isolates, decreased sensitivity was observed to be against the commonly used antibiotics such as amikacin (15.70%), gentamicin (13.90%), ampicillin + sulbactam (8.97%), and cefotaxime
Since the first report from Spain in 2000 of strains producing CTX-M-9 (6), which confers resistance to cefotaxime
, various CTX-M-type ESBLs have been identified in Salmonella Virchow.
KEY WORDS: Suppurative otitis media; Culture; Kirby-Bauer disc diffusion method; Pseudomonas aeruginosa; Staphylococcus aureus; Morganella morganii; Escherichia coli; Vancomycin; Ceftazidime; Cefotaxime
belongs to the third generation of Cephalosporin and we considered it as a drug model because of its wide-spectrum of antimicrobial activity and its excellent water solubility .