Avibactam is a first-in-class non-beta-lactam beta-lactamase inhibitor which protects ceftazidime
against degradation by certain beta-lactamases.
The following antibiotic discs were tested: Ceftazidime
(30 [micro]g), Cefotaxime (30 [micro]g), Ceftriaxone (30 [micro]g), Cefepime (30 [micro]g), Cefoxitin (30 [micro]g), Ampicillin (10 [micro]g), Gentamicin (10 [micro]g), Amikacin (30 [micro]g), Ciprofloxacin (5 [micro]g) and Meropenem (10 [micro]g) [HiMedia laboratories, Mumbai, India].
aeruginosa isolates were classified as ceftazidime
nonsusceptible (NS; MIC, >8 [micro]g/mL) and meropenem-NS (MIC, >2[micro]g/mL).
Intravenous (IV) ceftazidime
dose 1g OD and IV cloxacillin 500mg QID were commenced after blood cultures were taken from the catheter and peripheral site.
pneumoniae showed 100% resistance to amoxicillin-clavulanic acid, ceftazidime
, ceftriaxone, cefotaxime and aztreonam.
Antimicrobial discs of piperacillin/tazobactam (TZP; 100/10 ug/ml), amikacin (AK; 30 ug/ml), ciprofloxacin (CIP; 5 ug/ml), ceftazidime
(CAZ; 30 ug/ml), meropenem (MEM; 10 ug/ml) and aztreonam (ATM; 30 ug/ml) were obtained from Oxoid.
12 The antibiotics that were used against gram-positive bacteria were (20 ug of amoxicillin + 10 ug of clavulanate), ceftazidime
(30ug), cephalothin (30ug), clindamycin (2ug), erythromycin (15ug), gentamycin (10ug), oxacillin (1ug), penicillin (10ug) and vancomycin (30ug).
is one of the third-generation of cephalosporins, which can lead to development of Extended-Spectrum Beta-Lactamases (ESBLs) in gram negative bacteria such as Pseudomonas aeruginosa (P.
It consists of ceftazidime
, a thirdgeneration cephalosporin, and avibactam, a non-B lactam B-lactamase inhibitor.
Confirmatory test susceptibilities to cefotaxime and ceftazidime
alone those with clavulonate are compared using disk diffusion, increase significantly more than or equal to five mm increase in a zone diameter (7).
The aim of the research was to design a controlled drug release system by using dendrimer nanoparticles and ceftazidime
antibiotic to cure infections caused by gram negative bacteria such as pseudomonas aeruginosa.
Abstract: Bacterial culture and susceptibility testing results of a wound on the plantar aspect of the foot of a 4-year-old, male chicken with a class IV pododermatitis revealed a multidrug-resistant Escherichia coli bacterium, sensitive to only a few antibiotics including ceftazidime