cell cycle


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Related to cell cycle: cell division, mitosis, meiosis

cell cycle

n.
The series of events involving the growth, replication, and division of a eukaryotic cell.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

cell cycle

n
(Genetics) the growth cycle of eukaryotic cells. It is divided into five stages, known as G0, in which the cell is quiescent, G1 and G2, in which it increases in size, S, in which it duplicates its DNA, and M, in which it undergoes mitosis and divides
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

cell′ cy`cle


n.
the cycle of growth and asexual reproduction of a cell, consisting of interphase followed in actively dividing cells by prophase, metaphase, anaphase, and telophase.
[1970–75]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
merolae cell structures at each cell cycle phase is shown (upper panel), and DYNAMO2 localization in typical cells at each cell cycle phase (middle and lower panels) was assessed by immunofluorescence microscopy (lower panel).
The investigational assay will incorporate biomarkers from Zomedica's canine cancer research programs with IncellDx's core BioINK reagents and novel cell cycle capabilities on CTCs.
"SRA141 potently and selectively inhibits the cell division cycle kinase, Cdc7, thereby interfering with DNA replication and cell cycle dynamics within tumor cells while sparing normal cells.
Metformin also resulted in cell cycle arrest at G1 phase in breast adenocarcinoma cell line via decreasing Cyclin Dependent Kinases (CDKs) and the upregulation of Retinoblastoma (Rb) related proteins (p107 and p130).
DNA ploidy and cell cycle testing of tumors could return to the clinical laboratory.
Cyclin D1 causes the G1/S cell cycle transition to facilitate progression.[4] Our results of RT-PCR and Western blotting also showed that the expression of cyclin D1 significantly declined in MCL cells treated with wogonin [Figure 1]d and [Figure 1]e, which further reveals that wogonin could suppress the expression of cyclin D1.
PLK1 (Polo-like kinase 1) is a member of the Polo-like kinase family [1], which plays an important role in cell cycle regulation [2].
The study, which also included Fang-Yi Chu, an NYU doctoral candidate, and Shannon Haley, an NYU undergraduate, sought to expand our understanding of the cell nucleus during the cell cycle.
This senescence-associated DDR chronically turns on the machinery needed to repair breaks and errors in DNA, and activate cell cycle checkpoints, which inhibit cells from dividing.
Cellular senescence is due to cycle arrest in the G1 phase of the cell cycle in response to physiological levels of mitogens.
It is characterized by the presence of the distinctive forkhead DNA binding domain, a highly conserved winged helix motif, and regulates the transcription of genes involved in a variety of processes, including cell cycle regulation [2, 3], apoptosis [4, 5], DNA repair [6], and autophagy [7-9].
Cell cycle dynamics, including the progression and exit of cell cycle, is important in cell fate decisions during neurogenesis [18].

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