The second component to the immune system is called cell-mediated immunity
. This part of your cat's immune defenses involves the activation of various cells that either engulf invading pathogens or that release chemicals that ultimately lead to the recruitment of other cells in neutralization of pathogens.
Studies have shown that patients with poor glycaemic control (glycosylated haemoglobin [HbA1c]>7%) had an increased risk of TB activation compared to patients with normal glycaemic level.24 In DM hosts, there is a delay in activation of Th1 cell-mediated immunity
, leading to dysfunction in the adaptive immune response.28 In co-morbid TB-DM patients, increased levels of Th1 and Th17 cytokines are found.32 The efficacy of the Th1 response is reduced by impaired cellular interactions and the inability to mount a response during infections in DM hosts.
Effect of cardiopulmonary resuscitation-induced stress on cell-mediated immunity
. Intensive Care Med 1984;10:287-92.
Evaluation of Cell-mediated Immunity
by Delayed Type Hypersensitivity (DTH) Test
Our patient did not receive steroids or chemotherapy and had normal immunoglobulin levels, implying that the underlying defect was one in cell-mediated immunity
. Cell-mediated defects in patients with CLL have been described as both primary defects and chemotherapy-induced defects .
As the reader might guess, a measure of this diversity in a patient is a measure of the robustness of his or her cell-mediated immunity
As an indicator of susceptibility to infectious disease, cell-mediated immunity
was measured by antibody response to three vaccines and skin prick tests, white blood cell count, and self-reported illness.
The authors concluded that their findings indicated that cell-mediated immunity
is affected by the herpes zoster vaccine and enhanced by a stronger, or more recent, dose.
LADD is a proprietary platform of live-attenuated double-deleted Listeria monocytogenes strains that have been engineered to induce a potent innate immune response and to express tumor-associated antigens to induce tumor-specific T cell-mediated immunity
- Kits for virus-specific cell-mediated immunity
The Type 1 reaction (T1R) is a delayed hypersensitivity reaction associated with sudden alteration of cell-mediated immunity
associated with a shift in the patient's position in the leprosy spectrum.
Reduced cell-mediated immunity
was proposed as a potential explanation for the high incidence of head and neck cancer observed in alcoholic patients (Lundy et al.