centromere


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cen·tro·mere

 (sĕn′trə-mîr′)
n.
The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

cen′tro·mer′ic (-mĕr′ĭk, -mîr′-) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

centromere

(ˈsɛntrəˌmɪə)
n
(Genetics) the dense nonstaining region of a chromosome that attaches it to the spindle during mitosis
centromeric adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

cen•tro•mere

(ˈsɛn trəˌmɪər)

n.
a structure appearing on the chromosome during mitosis or meiosis, where the chromatids are joined in an X shape.
[1920–25]
cen`tro•mer′ic (-ˈmɛr ɪk, -ˈmɪər-) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

cen·tro·mere

(sĕn′trə-mîr′)
The region of the chromosome to which the spindle fiber is attached during mitosis. The centromere is where the chromatids join together in pairs before separating into individual chromosomes. See more at meiosis, mitosis.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.centromere - a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence"
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
chromosome - a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
centrómero
tsentromeer
References in periodicals archive ?
C, From another subject, an interphase nucleus showing 1 domain of chromosome 9 and 2 small domains (boxes) with distal 9p and 9q arm signals with color bands for 9p24.3, 9p21.2, and 9q34.3, with deletion of the interstitial segment including the centromere. D, A normal chromosome 9 and 2 previously unidentified "marker" chromosomes from the same case shown in (C), with the chromosome 9 color band ideogram for reference.
Here, we present a case of Roberts Syndrome brought to the clinic with diarrhoea and multiple abnormalities, that had tetra phocomelia, growth and developmental retardation, abnormality of complete cleft lip-palate accompanied with Aortic stenosis and PDA, and in which cytogenetic analysis identified premature centromere separation.
Nevertheless, it is well established that the centromere staining pattern is primarily associated with the limited cutaneous form of SSc (also referred to as the CREST syndrome) [8, 93].
One of the specific autoantibodies, such as anti-double-stranded DNA (anti-dsDNA), usually shows relatively low titers in ANA, whereas others, such as anti-U1RNP and centromere, may lead to very high titers of positive ANA, irrespective of the clinical and life-threatening severity.
The M4 carries a large block next to the centromere, with a smaller one distal to it, whereas the reverse situation occurs on the M6.
However, no one has studied centromere organization in sedges, and a detailed comparative study may be fruitful.
Mutational and in vitro protein-binding studies on centromere DNA from Saccharomyces cerevisiae.
speltoides segment is located 2 to 10 cM from the centromere and is 20 to 30 cM long (Dubcovsky et al., 1998).
On chromosome 5, the 5S rRNA genes were located immediately next to the centromere, whereas on chromosome 6, they were located approximately half way between the telomere and the centromere.
We selected 100 well-spread metaphases per animal from 5 slides for scoring the frequencies of cells with gaps and breaks, cells with at least one chromosome showing early separation of the centromere (early segregation), polyploid, and extremely damaged (i.e., with nuclear material visibly different from normal patterns of cell division stages).
Synapsis of the lateral elements of the trivalents proceeded unidirectionally from both sets of telo-meres of the metacentric element towards the centromere [ILLUSTRATION FOR FIGURE 2A OMITTED].