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Related to centromeric: kinetochore, telocentric chromosome


The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

cen′tro·mer′ic (-mĕr′ĭk, -mîr′-) adj.
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Adj.1.centromeric - pertaining to the dense specialized portion of a chromosome to which the spindle attaches during mitosis
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References in periodicals archive ?
colombica, (Table 1) with heterochromatin in the interstitial region of 4 chromosomes added to the centromeric heterochromatic blocks on all the chromosomes (Murakami et al.
The detection of the centromeric position and the measurement of arm lengths was found to be relatively difficult for some of the chromosomes and for this reason only the total length of the chromosomes are being reported here (Table 3).
The data indicate the presence of 2 distinct breakpoint cluster regions: centromeric of RB1 in myeloid malignancies and distal to RB1 in some lymphoid B-cell and T-cell malignancies.
45 Furthermore, SNP mapping of the MHC region of anti-CCP positive RA patients has identified additional independent risk in the centromeric region of the HLA-DRB1 locus, which includes the HLA-DOB (beta chain), antigen peptide transporter 2 (TAP2), HLA-DPB1 and collagen type X1 alpha2 (COL11A2) genes.
In addition, in Chinese workers exposed to high doses of benzene (Greater than 10 ppm), exposure appears to increase terminal duplications and deletions for chromosome 1 and increase centromeric duplications and deletions for chromosome 1 in sperm (Liu XX et al.
Loss of centromeric histone H3 (CENH3) from centromeres precedes uniparental chromosome elimination in interspecific barley hybrids.
Isolation and molecular characterization of a highly polymorphic centromeric tandem repeat in the family Falconidae.
The DRA gene is located at the most centromeric of SLA II gene cluster, encodes the a chain with DQA gene.
Based on rheumatologic and seroimmunological examination findings, the patient was found to have a high titer of antinuclear antibody (1:1280) with a centromeric pattern, and positive anticentromere-B antibodies (> 8.
The inner kinetochore directly binds to the centromeric chromatin during the whole cell cycle.
We further filtered reads that aligned to the mitochondrial genome or centromeric regions, and we selected specifically for putative interchromosomal translocation events.
In particular, our recent work demonstrated that mislocalization of the centromeric histone variant CenH3 gives cells an adaptive advantage to overcome DNA damage induced by camptothecin treatment and gamma irradiation.