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Related to centromeric: kinetochore, telocentric chromosome


The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

cen′tro·mer′ic (-mĕr′ĭk, -mîr′-) adj.
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Adj.1.centromeric - pertaining to the dense specialized portion of a chromosome to which the spindle attaches during mitosis
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References in periodicals archive ?
The chromosome 3 copy number was assessed using the ZytoDot digoxigenin-labeled CEN 3 centromeric probe from Zytovision (Bremerhaven, Germany) and detected using the ZytoDot CISH Implementation Kit, also from Zytovision.
Multiplex PCR results showed a deletion involving the IL1RAPL1 gene at the telomeric end of the deletion and extending into the DMD gene at its centromeric end (Fig.
Chromosomes were classified according to their centromeric index and arranged by decreasing size (Levan et al.
A common major QTL for CGA accumulation was detected in all three populations in the centromeric region of chromosome 2.
Mys sequences were absent from the heterochromatic segments of the autosomes and from the centromeric region of the X chromosome.
In these cases, additional analysis with the D3Z1 chromosome 3 centromeric probe revealed no evidence of chromosome 3 aneuploidy, consistent with BCL6 amplification.
The first deletion hot spot overlapped the commonly deleted region (10p14-15) reported in other studies (9,10,14), but somewhat extended to the centromeric side.
Measurements were used to determine relative lengths of chromosomes (length of the chromosome pair / total complement length x 100) and centromeric index (length of short arm / total length of the chromosome x 100) of each chromosome.
Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation.
1964), based on the centromere position, assessed in this work through the determination of the centromeric index (short arm length (p)/total chromosome length (p+q)), was followed to classify chromosomes.
Fluorescence in situ hybridization (FISH) for EGFR was performed on paraffin sections using Vysis probe locus-specific identifier (LSI) EGFR 7p12 Spectrum Orange probe and Spectrum green-labeled centromeric CEP7 using standard protocols (Abbott Diagnostics, Abbott Park, Illinois).
A total of 356 chromosomes were randomly measured and their centromeric index was calculated (100 x length of short arm/total chromosome length).