Surprisingly, little information is available on microtubule and centrosome
behavior in early development of oysters and especially Crassostrea virginica.
Estrogen mediates aurora- a overexpression, centrosome
amplification, chromosomal instability and breast cancer in female ACI rats.
BBS is a disease under the spectrum of 'ciliopathies' because molecular basis for this disease is that it affects the centrosome
and affect the ciliary transport.
Aurora A kinase is required for centrosome
maturation, separation, and function (Glover et al.
Some cellular proteins have a dual role in autophagy and centrosome
stability; a normal number of centrosomes
is important for brain development (online Technical Appendix reference 54).
Loss of the forkhead transcription factor FoxM1 causes centrosome
amplification and mitotic catastrophe.
play crucial roles in many processes (including organizing mitotic spindle poles), and centrosome
aberrations (Nigg 2002) are included in many human tumors (Rusan and Peifer 2007).
abnormalities in head and neck squamous cell carcinoma (HNSCC).
BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome
localization," Cancer Science, vol.
It was previously proposed that nucleokinesis occurs in two steps, based on observations of neurons from the SVZa of rats on postnatal day (P) 0-2 cultured in Matrigel: first, forward movement of the centrosome
, which is often associated with the Golgi apparatus, and second, forward movement of the nucleus (Fig.
Pathway#: 1 = cell extracellular matrix interactions; 2 = alpha-linolenic acid metabolism; 3 = metabolism of lipids and lipoproteins; 4 = VEGF signaling pathway; 5=P75NTR recruits signaling complexes; 6 = endocytosis; 7 = P75NTR signals via NFKB; 8 = hormone ligand binding receptors; 9 = set pathway; 10 = linoleic acid metabolism; 11 = notch HLH transcription pathway; 12 = long term depression; 13 = FC epsilon RI signaling pathway; 14 = AKAP centrosome
pathway; 15 = NA CL dependent neurotransmitter transporters; 16 = activated TAK1 mediates P38 MAPK activation; 17 = ABC transporters; 18 = amino acid transport across the plasma membrane; 19 = amyotrophic lateral sclerosis (ALS); 20 = other glycan degradation.
Materials of the research included Ultisol soil in South Sulawesi, Centrosema pubescens compost, elephant grass compost, chicken manure compost, humic compounds of the Centrosome
pubescens compost, humic compounds of the elephant grass compost, and humic compounds of the chicken manure compost.