cephalothin


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Related to cephalothin: cephalexin, cefazolin, cefuroxime, ceftriaxone, gentamicin

cephalothin

(ˈsɛfələˌθɪn)
n
a cephalosporin antibiotic often used in the treatment of bacterial infections
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Noun1.cephalothin - a semisynthetic analogue of cephalosporin
cephalosporin, Mefoxin - one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity
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Contract awarded for cephalothin, injectable solution or powder for parenteral use 1 g vial or ampule
5 >32 Cephalothin >64 32 >64 Meropenem <1 <1 <1 Imipenem <2 <2 <2 Piperacillin/tazobactam <4 <4 <4 Streptomycin >128 4 4 Tetracycline 128 <2 <2 Chloramphenicol 8 8 8 Trimethoprim/sulfamethoxazole >16 <1 <1 Gentamicin 2 <1 <1 Amikacin <4 <4 <4 Azithromycin 1 1 1
The antibiotic tested included ampicillin (10 pg), ciprofloxacin (5 [micro]g), chloramphenicol (30 [micro]g), trimethoprim (5 [micro]g), cephalothin (30 [micro]g), streptomycin (10 [micro]g), nalidixic acid (30 [micro]g), and tetracycline (30 pg).
AmpC beta-lactamases are clinically important cephalosporinases, confer resistance to cephalothin, cefazolin, cefoxitin, most penicillins and [beta]-lactamase-[beta]-lactamase inhibitor combinations.
This effect is low compared to that of Gentamicin and Cephalothin used as antibiotics reference.
coli O157: H7 isolated from meat and meat products in Gabone, Botswana, were resistant to cephalothin, sulfatriad, colistin sulfate and tetracycline [31].
All isolates were resistant to the antimicrobial agents cefazolin (CZ), cefotaxime (CTX), cephalothin (CF), doxycycline (D), nalidixic Acid (NA), and oxacillin (OX).
coli isolates for their resistance to various antibiotics: rifampicin, tetracycline, erythromycin, cephalothin, streptomycin, ampicillin, and amoxicillin clavulanate.
Susceptibility profile was tested by disc-diffusion agar (CLSI 2009) with the following drugs: amikacin, ampicillin, ampicillin + sulbactam, cephalothin, cefoxitin, cefpime, caeftazidime, ceftriaxone, gentamicin, imipenem, meropenem, piperacillin, quinolones, and sulfazotrim ticarcillin + clavulanic acid (Table 1).
Cephalothin and cefazolin in vitro antibacterial activity and pharmacokinetics in dogs.
Probiotic candidate OY15 was susceptible to 10 of the antibiotic disks, showing intermediate susceptibility to neomycin (5 lag) and trimethoprim (5 lag), and exhibiting resistance to ampicillin (10 lug) as well as cephalothin (30 lug).
One subject who underwent vertebroplasty and could not receive prophylactic cephalothin because of drug allergies developed an adjacent new fracture and osteomyelitis requiring surgery.