In relation to the type of lesion, the frequency of clinical signs and symptoms was highest among the patients with primary tumors, whereas the absence of nausea, vomiting, cerebellar syndrome
was observed in the patients with secondary tumors, and only one patient was recorded with organic brain syndrome, headache, seizure and speech disorders.
The diagnosis of probable or possible MSA-C was established based on the second consensus criteria:[sup] (1) a sporadic, progressive, and adult (>30 years) onset disease characterized by a cerebellar syndrome
(gait ataxia with cerebellar dysarthria, limb ataxia, or cerebellar oculomotor dysfunction), and (2) at least one of the additional features as follows: parkinsonism (bradykinesia and rigidity); atrophy of putamen, middle cerebellar peduncle, or pons on magnetic resonance imaging (MRI); hypometabolism on fluorodeoxyglucose-positron emission tomography (FDG-PET) in putamen; and presynaptic nigrostriatal dopaminergic denervation on single photon emission computed tomography (SPECT) or PET.
Neurological examination revealed cerebellar syndrome
findings in all cases.
We report two patients presenting two different forms of MSA, although in the first case cerebellar syndrome
was the main feature and in the second case, parkinsonian symptoms were predominant.
Criteria for possible MSA include parkinsonism or a cerebellar syndrome
in addition to symptoms of MSA listed in the Table, whereas probable MSA has specific criteria of either a poorly levodopa-responsive parkinsonism (MSA-P) or a cerebellar syndrome
symptoms included global cerebellar syndrome
, pyramidal, visual
Finally, more recently, JCV was linked with cerebellar syndrome
in HIV infected patients.
The first clinical sign is typically a feeling of unsteadiness, experienced usually as vertigo or balance impairment; Cerebellar syndrome
gradually develops, as well as--albeit to a different degree--dorsal columns symptomatology.
A delayed onset cerebellar syndrome
complicating falciparum malaria.
Peripheral neuropathy , epilepsy , cerebellar syndrome
 myopathy and hyporeflexia  have all been reported in association with coeliac disease.