cerebellar syndrome


Also found in: Medical.

cerebellar syndrome

n
(Pathology) a disease of the cerebellum characterized by unsteady movements and mispronunciation of words. Also called: Nonne's syndrome
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[2,3,13] The most common clinical features are seizure (60-75%), [3,14,15] headache (50%), [16,17] encephalopathy (5080%), [18,19] visual disturbances (33%), [6,14] focal neurological deficit(10-15%) [14,20] and status epilepticus (5-15%) [3,14] Focal neurological deficit, such as cortical blindness, cerebellar syndrome or hemiparesis may lead to coma.
Adult celiac disease presenting as cerebellar syndrome. Neurology 1980; 30(3):245-249.
The age of onset is similar with MS and in the case of progressive cerebellar syndrome, diagnosis of Wilson's disease should be considered especially because it is a treatable disease (8).
These focal disorders can include motor and sensory loss with hemiparesis, aphasia, dysarthria, seizures, movement disorders, and cerebellar syndrome. The most common focal presentation in our patients was seizures which occurred in 34.6% of our patients.
Adams, Schatzki, & Scoville (1941) recognized five syndromes into which these deficits could be grouped: Intracranial hypertension syndrome, cranial nerve impairment, bulbar compression syndrome, medullary syndrome and cerebellar syndrome.
Cytarabine-induced cerebellar syndrome: Case report and literature review.
Hypomagnesemia may also lead to a wide spectrum of neurological disorders, such as primary downbeat spontaneous nystagmus with ataxia [4-6], cerebellar syndrome [7-9], myopathy [10], and posterior reversible encephalopathy syndrome (PRES) [11, 12].
EDSS = 3 Patient 3 Dysarthria + static and kinetic cerebellar syndrome. EDSS = 3 Patient 4 Dysarthria + dystonia + cerebellar syndrome + proprioceptive dysfunction + nystagmus + 7th nerve paralysis + decreased vision.
Given the primary cerebellar syndrome presented here, the case supports continued investigation into cerebellar involvement as the underlying pathophysiology leading to PBA.
In relation to the type of lesion, the frequency of clinical signs and symptoms was highest among the patients with primary tumors, whereas the absence of nausea, vomiting, cerebellar syndrome was observed in the patients with secondary tumors, and only one patient was recorded with organic brain syndrome, headache, seizure and speech disorders.
The previous studies suggested that RBD was considered as a red flag for the diagnosis of MSA [sup][30] and might either antedate or follow the onset of parkinsonism, cerebellar syndrome, and dysautonomia [sup][31] that might be due to inchoate structural lesion which damages REM regulating regions of brain (lower brainstem and limbic system mainly).[sup][32] The occurrence of RBD in MSA suggested that the brainstem was involved in the process of the disease.
Criteria for possible MSA include parkinsonism or a cerebellar syndrome in addition to symptoms of MSA listed in the Table, whereas probable MSA has specific criteria of either a poorly levodopa-responsive parkinsonism (MSA-P) or a cerebellar syndrome (MSA-C).