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n.1.(Med.) A hypochondriacal condition verging upon insanity, occurring in those whose brains have been unduly taxed; - called also brain fag.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
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Among industrialized countries, Japan has by far the highest number of magnetic resonance imaging and CT scanners used per head of population (Organization for Economic Co-operation and Development, 2011), and efforts to screen asymptomatic cerebropathy have been promoted since early 1990 (Yoshimoto & Mizoi, 1997).