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Noun1.cerivastatin - an oral drug (trade name Baycol) to reduce blood cholesterol levelscerivastatin - an oral drug (trade name Baycol) to reduce blood cholesterol levels
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
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References in periodicals archive ?
Cerivastatin monotherapy-induced muscle weakness, rhabdomyolysis and acute renal failure.
Examples include cholesterol drugs cerivastatin (Baycol) and simvastatin (Zocor).
Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study.
Sugiyama, "Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A," The Journal of Pharmacology and Experimental Therapeutics, vol.
The studies which were included in this meta-analysis should meet the following criteria: (1) the design of studies should be controlled strictly, including case-control studies, cohort studies, and RCTs; (2) no prior diagnosis of any cancer prior to the date of cancer diagnosis; (3) studies should specific one or more types of statins, including rosuvastatin, atorvastatin, simvastatin, pravastatin, fluvastatin, cerivastatin, and lovastatin; (4) studies should be designed to evaluate the impact of statins on the risk of cancers with T2DM; (5) studies should have provided sufficient information to calculate odds ratios (ORs) and 95% confidence intervals (CIs).
A retrospective review of the FDA Adverse Event Reporting System (AERS) database found that 88% of fibrate and statin combinations that resulted in rhabdomyolysis were associated with gemfibrozil/cerivastatin (cerivastatin is no longer available in the United States).
Redmond, "Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance," Surgical Infections, vol.
Renzo, "Hypercoagulable state inhypercholesterolemic subjects assessed by platelet dependent thrombin generation: in vitro effect of cerivastatin, European review formedical and pharmacological sciences," 'European Review Formedical And Pharmacological Sciences, vol.
Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin. FASEB J 2002; 16: 1928-30.
Several medicines were withdrawn from the market due to their interaction with other substances (mainly related to the CYPs) for example: Seldane[R] (Terfenadine, Aventis Pharmaceuticals, USA), Posicor[R] (Mibefradil, Roche, Switzerland), Propulsid[R] (Cisapride, Janssen-Ortho, Canada), Lotronex[R] (Alosetron, Prometheus Laboratories Inc., USA), Baycol[R] (Cerivastatin, Bayer A.G., Germany) and Serzone[R] (Nefazodone, Bristol-Myers Squibb, USA) (25).