Does oxidative stress change ceruloplasmin
from a protective to a vasculopathic factor?
Serum trace metal and ceruloplasmin
variability in individuals treated for pulmonary tuberculosis.
The present study was done to evaluate oxidative stress in GDM by estimating serum levels of MDA (oxidant), serum ceruloplasmin
(antioxidant), and uric acid (antioxidant).
Serum electrolytes, iron, copper, and ceruloplasmin
levels were within normal limits.
is an important acute phase protein which activates under stressful conditions.
Total oxidant--antioxidant statuses, ceruloplasmin
, and ischemia-modified albumin (IMA) are among important biomarkers of oxidative stress.
Copper and iron interact through the ceruloplasmin
, a copper-dependent oxidase, which assists in iron transport in the plasma in association with transferrin by oxidation of Fe2+ into Fe3+ .
The patient's serum levels of copper and ceruloplasmin
Plasma Copper, Serum Ceruloplasmin
, and Lipid Profile.
Therefore, apolipoprotein A-II (APOA2) and ceruloplasmin
(CP) may be involved in the development of PDR and in the mechanism of the effects of anti-VEGF treatment.
In this context, ceruloplasmin
, the primary plasmatic copper carrier, plays a pivotal role in preventing the formation of extracellular ROS by oxidizing [Fe.sup.2+] to [Fe.sup.3+], thereby promoting the sequestration of iron by apotransferrin [17, 18].
Antioxidant potential, paraoxonase 1, ceruloplasmin
activity and C-reactive protein concentration in diabetic retinopathy.