chaperonin


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Related to chaperonin: GroEL

chap·er·o·nin

 (shăp′ə-rō′nĭn)
n.
Any of a family of large chaperone proteins that function chiefly to assist in the folding of newly synthesized proteins.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Structure and function of a protein folding machine: The eukaryotic cytosolic chaperonin CCT.
chauvoei, such as enolase, chaperonin, ribosomal protein L10, flavoprotein, and glycosyl hydrolase, which showed protective antigenicity in other bacteria.
Saibil, "Structures of unliganded and ATP-bound states of the Escherichia coli chaperonin GroEL by cryoelectron microscopy," Journal of Structural Biology, vol.
Also, the 60kDa heat shock protein is a chaperonin mainly involved in mitochondrial protein folding and translocation, but it is also suggested as a danger signal of stressed or damaged cells [54].
A newly designed loop-mediated isothermal amplification (LAMP) assay based on cpn60 (encoding for chaperonin 60) was carried out in a total volume of 25 [micro]L containing 0.5 [micro]L each of pho-F3 and Pyo-B3 primer (25pmol/[micro]L) equivalent to 0.5 [micro]M final concentration, 1 [micro]L each of Pyo-LoopF and Pyo-LoopB primer (25pmol/[micro]L) equivalent to 1.0 [micro]M final concentration, 2 [micro]L each of Pyo-FIP and Pyo-BIP primer (25pmol/[micro]L) equivalent to 2.0 [micro]M final concentration, and 15 [micro]L Isothermal Master Mix Iso-001 (Optigene, Horsham, UK).
Purification and characterization of 60 kD lipase linked with chaperonin from Pseudomonas aeruginosa BN1.
Frydman, "Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets," Trends in Cell Biology, vol.
Miki, "Crystal structures of the group II Chaperonin from thermococcus strain KS-1: steric hindrance by the substituted amino acid, and inter-subunit rearrangement between two crystal forms," Journal of Molecular Biology, vol.
Additionally, heat shock protein 60 (Hsp60), a mitochondrial chaperonin involved in stress responses, diabetes, and immunological disorder, has structural similarity to thyroglobulin and thyroid peroxidase molecules.
MERVL and Zscan4 have recently been reported to be associated with DNA demethylation in the nuclear [33], while the expression of Hsp70.1 (known as a chaperonin) and eIF-1A may affect the process of posttranscriptional regulation in the cytoplasm; thus, the detection of the combination of these four factors may well reflect the cell state.