chemoattractant


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chemoattractant

(ˌkɛməʊəˈtræktənt)
n
(Biochemistry) a chemical substance that provokes chemotaxis, esp one that causes a bacterium to move in the direction in which its concentration is increasing
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
ChemoCentryx targets the chemokine and chemoattractant systems to discover, develop and commercialize orally-administered therapies.
Among them, monocyte chemoattractant protein-1 (MCP-1/CCL2) is known as a downstream molecule following prostaglandin stimulation (12).
After 72 hours, the culture media of the cells were collected and maintained at -80[degrees]C to use in invasion/migration experiments as chemoattractant.
ChemoCentryx's Kidney Health Alliance with Vifor Pharma provides Vifor Pharma with exclusive rights to commercialise avacopan and CCX140 in markets outside of the US ChemoCentryx also has early stage drug candidates that target chemoattractant receptors in other inflammatory and autoimmune diseases and in cancer.
To achieve this purpose, the impact of FR in mice receiving HFD or HCD during 56 days on serum levels of basic fibroblast growth factor (FGF-basic), granulocyte-macrophage colony-stimulating factor (GM-CSF), inducible protein 10 (IP-10), interferon [gamma] (IFN-[gamma]), interleukin 1[alpha] (IL-1[alpha]), IL-1[beta], IL-2, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, IL-17, keratinocyte chemoattractant (KC), macrophage inflammatory protein-1[alpha] (MIP-1-[alpha]), monocyte chemotactic protein 1 (MCP-1), monokine induced by IFN-[gamma] (MIG), and tumor necrosis factor [alpha] (TNF-[alpha]) were evaluated.
The researchers found that the odds of incident CKD increased with higher concentrations of urinary albumin, kidney injury molecule-1, and monocyte chemoattractant protein-1 at baseline (adjusted odds ratio per doubling: 1.50, 1.51, and 1.70, respectively).
Based on the literature, the adipokines that are elevated in psoriasis patients, compared with controls, include leptin, TNF-alpha, resistin, interleukin-6, and monocyte chemoattractant protein-1.
(8) Dapsone also appears to inhibit chemoattractant signaling, which prevents neutrophil recruitment at the site of inflammation.
The fact of finding no statistical differences from the first bioassay results with pelletized ingredients could be because the chemoattractant efficiency is related to its diffusion coefficient and its water solubility as stated by Lee & Meyers (1996).
Both treatments increased fasting and postprandial PON1 activity and decreased postprandial monocyte chemoattractant protein 1 concentrations.
Such modulators of inflammation include proinflammatory cytokines (e.g., interleukin 1[beta] (IL-1[beta]) [28], iL-6 [29,30], IL-18 [31]) and monocyte chemoattractant protein-1 (MCP-1 [32]) as well as the proteolytic release of the anti-inflammatory molecule, N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) from thymosin [beta]4 [33].