Several studies have proven the chemopreventive
effects of phytochemicals derived from fruits and vegetables.
agents are recognized in various epidemiological, preclinical, and clinical studies.
Data on its antioxidant and chemopreventive
properties also have prompted investigations into its potential in the dermatologic realm because sesamol has demonstrated an increasingly wide array of cutaneous applications.
Castanea sativa Mill, bark extract exhibits chemopreventive
properties triggering extrinsic apoptotic pathway in Jurkat cells.
"Aspirin has been investigated to explore its chemopreventive
effect in cancers that are related to chronic inflammation, particularly in the prevention of colorectal cancer.
The systematic review and meta-analysis of published randomised controlled trials (RCTs) was conducted to review the effectiveness of current chemopreventive
agents in the treatment of oral leukoplakia lesions (OPLs) and prevention of their progression to oral cancer.
The use of a chemopreventive
agent to prevent breast cancer in patients who have not had a previous diagnosis of breast cancer is termed primary chemoprevention.
The objective of this study was to determine the chemopreventive
properties of GRR crude extract in Sprague-Dawley rats induced with azoxymethane (AOM).
"An ideal chemopreventive
agent with its low toxicity, affordability, and easy accessibility"2
'Together, our findings demonstrate preclinical chemopreventive
activity of sulforaphane against carcinogen-induced oral cancer, and support further mechanistic and clinical investigation of sulforaphane as a chemopreventive
agent against tobacco-related HNSCC [head and neck squamous cell carcinoma].'
-- A single course of topical 5-fluorouracil (5-FU) prevented 62% more actinic keratoses than placebo, and this chemopreventive
effect persisted for up to 3 years, according to an analysis of the Veterans Affairs Keratinocyte Carcinoma Chemoprevention Trial (VAKCCT) trial.