The expert said at least 25 per cent of children with malaria a national survey found were still being treated with chloroquine
, an ineffective antimalaria drug, and urged medical experts to desist from doing so.
They detailed a potent chloroquine
, known as DC661, that can take advantage of this new treatment pathway.
vivax resistance to chloroquine
has emerged more recently; the first cases were observed in 2009 in Rattanakiri Province in northeastern Cambodia (17.4% treatment failures after 28 days of follow-up), which led to withdrawal of chloroquine
and use of dihydroartemisinin/piperaquine (DHA/PPQ) as first-line therapy for uncomplicated P.
The research, led by WCM-Q's Dr Anna Halama and Dr Karsten Suhre, analysed the metabolic processes of cancer cells to show that the quinine-based malaria drug Chloroquine
could boost the effectiveness of glutaminase inhibiting drugs, which are currently being developed by pharmaceutical firms.
Karsten Suhre, analyzed the metabolic processes of cancer cells to show that the quinine-based malaria drug Chloroquine
could boost the effectiveness of glutaminase inhibiting drugs, which are currently being developed by global pharmaceutical companies.
A switch to chloroquine
, or adding quinacrine, might do the trick, saving at least some patients from having to move on to immunosup pressive therapy, Dr.
(ClQ) is a Schizontocidal drug, which has a strong and rapid for the treatment and prevention of clinical symptoms (Bruce-Chwatt, 1962).
Three subsequently infected snowy owls have been treated with primaquine and chloroquine
. The birds that were treated survived infection, and parasite burdens in peripheral blood diminished.
These included Plasmodium falciparum multidrug resistance 1 (pfmdr1), Plasmodium falciparum multidrug resistance protein 1 (pfmrp1), and Plasmodium falciparum chloroquine
resistance transporter (pfcrt).
In Cameroon, malaria treatment guidelines have evolved since 2002 from the use of chloroquine
through the use of amodiaquine and sulphadoxine-pyrimethamine to artemisinin-based combination therapy .
Patients with chloroquine
resistance/Falciparum malaria/complicated malaria received artesunate injections.