Also found in: Thesaurus, Medical, Wikipedia.
Related to chlorothiazide: furosemide


A thiazide diuretic, used also in its sulfate form to treat hypertension, congestive heart failure, and edema.


(Pharmacology) a diuretic drug administered orally in the treatment of chronic heart and kidney disease and hypertension. Formula: C7H6ClN3O4S2
[C20: from chloro- + thi(o-) + (di)az(ine + diox)ide]


(ˌklɔr əˈθaɪ əˌzaɪd, ˌkloʊr-)

a white, crystalline, slightly water-soluble powder, C7H6ClN3O4S2, used as a diuretic and in treating hypertension.
[1955–60; chloro-2 + thiaz (ole) + -ide]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.chlorothiazide - a diuretic drug (trade name Diuril) used in the treatment of edema and hypertension
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
thiazide - any of a group of drugs commonly used as diuretics in the treatment of hypertension; they block the reabsorption of sodium in the kidneys
References in periodicals archive ?
Specific diuretics Class Drug Comments Thiazide Chlorothiazide Chlorthalidone Thiazide-like in action, not in structure Hydrochlorothiazide Prototypical drug Hydroflumethiazide Indapamide Thiazide-like in action, not in structure Methyclothiazide Metolazone Thiazide-like in action, not in structure Polythiazide Loop Bumetanide Ethacrynic acid Furosemide Torsemide K+-sparing Amioloride Distal tubule [Na.
The two commonly used agents in clinical practice are chlorothiazide and hydrochlorothiazide.
Inadequate diuretic response may indicate the need to increase the dose of the loop diuretic, to add a second diuretic (such as metolazone, chlorothiazide, or spironolactone) to the loop diuretic, or to consider continuous infusion of the loop diuretic.
Neonatal megakaryocytic hypoplasia is caused by infection with cytomegalovirus (CMV), Toxoplasma, rubella, and human immunodeficiency virus (HIV) and in utero exposure to chlorothiazide diuretics and the oral hypoglycemic tolbutamide.
Examples: furosemide (Lasix), chlorothiazide (Diural), and hydrochlorothiazide (Dyazide).