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1. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
2. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.

[(acetyl)cholin(e) + -ergic.]

cho′li·ner′gi·cal·ly adv.


1. (Physiology) denoting nerve fibres that release acetylcholine when stimulated
2. (Physiology) of or relating to the type of chemical activity associated with acetylcholine and similar substances
[C20: from (acetyl)cholin(e) + Greek ergon work]


(ˌkoʊ ləˈnɜr dʒɪk, ˌkɒl ə-)

1. resembling acetylcholine in physiological effect: a cholinergic drug.
2. releasing acetylcholine: a cholinergic neuron.
3. activated by acetylcholine: a cholinergic receptor.
[1930–35; (acetyl) choline + -ergic]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.cholinergic - releasing or activated by acetylcholine or a related compound
anticholinergic - inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"
References in periodicals archive ?
This study looked at cholinergic neurons that are responsible for producing the brain chemical acetylcholine, which is released by cholinergic nerve cells to send signals from one neuron to another.
Background: Whether cholinergic innervations and/or autophagy have a role in the etiopathology of benign prostatic hyperplasia (BPH) is still unknown.
Browse Glaucoma Therapeutics Market by Drug Class (Alpha Agonist, Beta Blockers, Carbonic Anhydrase Inhibitor, Cholinergic, Combined Medication, Prostaglandin Analogs), End Users (Ambulatory Surgical Centers, Hospitals, Ophthalmic Clinics) and Forecast 2017-2021 at https://www.
It is also an intermediate of the phosphatidylinositol cycle, a second-messenger neuronal signaling system used by noradrenergic, serotonergic, and cholinergic receptors.
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system.
Purpose: In the present study, we sought to determine the effects of GBE on CCH-induced neuroinflammation and cholinergic dysfunction in a rat model of bilateral common carotid artery occlusion (BCCAo).
Acetylcholine is delivered to the amygdala by cholinergic neurons that reside in the base of the brain.
3-9) Scopolamine blocks central muscarinic cholinergic receptors, which reduces production of glutamate receptors and leads to reduced glutamate transmission and neurotoxicity.
This contracting agent is a synthetic choline ester that acts as a nonselective cholinergic agonist.
The first section discusses both general mechanisms acting on voltage-gated sodium and potassium channels and cholinergic receptors and specific mechanisms of palytoxin, maitotoxin, domoic acid, azaspiracids, and yessotoxins.
The alpha3beta4 NNR is located throughout the gastrointestinal tract and, when modulated, is believed to increase cholinergic tone, which in turn leads to increased motility.
The observed spasmolytic, bronchodilator, and vasodilator effects on the part of The extract were likely to be mediated through Ca+2 channel blocking activities, whereas observed contractile response in isolated guinea-pig ileum preparations was likely to be mediated through cholinergic agonistic activity.