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 (kō′lə-nĕs′tə-rās′, -rāz′)
Any of several enzymes that catalyze the hydrolysis of esters of choline, especially acetylcholinesterase.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌkəʊlɪˈnɛstəˌreɪs; ˌkɒl-)
(Biochemistry) an enzyme that hydrolyses acetylcholine to choline and acetic acid
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, ˌkɒl ə-)

an enzyme, found esp. in the heart, brain, and blood, that hydrolyzes acetylcholine to acetic acid and choline.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cholinesterase - an enzyme that hydrolyses acetylcholine (into choline and acetic acid)
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. colinesterasa, familia de enzimas.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
Request for the Report Summary: Cholinesterase inhibitors will remain the topselling drugs for treating lewy body dementia, accounting for nearly 60% share in 2018.
The cholinesterase inhibitors prevent the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine, which plays a role in attention, learning memory and other functions.
The results confirmed their hypothesis: teens who had lower AChE activity, suggesting greater exposure to cholinesterase inhibitors, showed more symptoms of depression assessed using a standardised depression assessment tool.
* A literature review identified published and unpublished randomized controlled trials in English and Chinese in which cholinesterase inhibitors were compared with placebo or another drug for treating delirium in non-critically ill patients.
Theoretically, cholinesterase inhibitors can cause some cardiovascular effects, including bradycardia, conductive block, and QT prolongation [6,7], because the heart is rich in cholinesterase.
Cholinesterase inhibitors, drugs used to treat Alzheimer's, are known to increase blood flow to the brain about 10-15 percent in humans.
The aim of the study was to evaluate the benefit of serial estimation of serum cholinesterase levels in patients with organophosphorous poisoning and correlation of serum cholinesterase levels with clinical severity, monitoring clinical course and predicting the outcome along with the analysis of other parameters.
Other treatment modalities, such as administration of whole blood, fresh frozen plasma, and human serum cholinesterase, have been attempted to hasten the recovery.
Should you ever need to take a cholinesterase inhibitor, there are FDA-approved options.
The second randomized to 20 mg memantine or placebo plus any existing cholinesterase inhibitor (ChEI).
Key clinical point: The combination of memantine and a cholinesterase inhibitor significantly improved behavioral symptoms compared to monotherapy in patients with moderate-severe Alzheimer's.