taurocholic acid

(redirected from cholyltaurine)
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tau·ro·cho·lic acid

 (tôr′ō-kō′lĭk, -kŏl′ĭk)
n.
A conjugate of taurine and cholic acid, C26H45NO7S, whose sodium salt is a component of bile.

[Greek tauros, bull (from its having been obtained first from ox bile); see tauro- in Indo-European roots + cholic acid.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

tau′ro•cho′lic ac′id

(ˌtɔr əˈkoʊ lɪk, -ˈkɒl ɪk)
n.
an acid, C26H45NO7S, occurring as a sodium salt in the bile of humans and certain carnivorous animals.
[1855–60; taur(ine2) + -o- + cholic acid]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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However, the authors could not clarify if the effect was due to a reduced liver uptake of cholyltaurine or caused by a reduced canalicular efflux (thus increasing the hepatocyte exposure to the drug), or both.
In our study, the administered dose of sodium fusidate was 30 mg x [Kg.sup.-1], which is comparable to the dose previously used by Bode (54 mg x [Kg.sup.-1] ip) [35] to study the effect of fusidate on cholyltaurine transport in the rat liver.
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