Biopsy reveals sheets of chondroblast
with background of chondroid matrix.
Failure of this process initiates chondroblast
and osteoclast activity and subsequent graft tissue absorption .
BMP-2 regulates growth and induces osteoblast and chondroblast
differentiation, while FGF-1 controls cell migration and proliferation.
Some authors suggested that FeLV may be related to the etiology of feline osteochondromas (POOL & CARRIG, 1972; DOIGE, 1987; ROSA & KIRBERGER, 2012), and viral particles have been observed in proliferated chondroblast
membranes (POOL & CARRIG, 1972).
Ultrastructurally Cells show primitive features to mature features ranging from prelipoblast and chondroblast
, to lipoblast and preadpoytes, to mature adipocyte.
Calastrini et al., "Effects of interleukin-1[beta] on chondroblast
viability and extracellular matrix changes in bovine articular cartilage explants," Biomedicine & Pharmacotherapy, vol.
Runx2 is a key regulator of chondroblast
and osteoblast differentiation and of bone development in vivo [18, 46].
Imamura et al., "Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast
differentiation," Molecular Biology of the Cell, vol.
(13) Histologically, the basic proliferating cell is chondroblast
, which has distinct oval nuclei with longitudinal groove.
IGF-I and IGF-II increases proliferation and differentiation of bone marrow progenitors to osteoblast and chondroblast
(Singh et al., 2007d) and myogenic satellite cells to adipoblast (Singh et al., 2007c) in vitro.
(a), chondrocyte (b), from tendon with cartilago sesamoidea.
In chondrosarcoma, the smears were cellular and contain chondroblast
, chondroid matrix forming amorphus background in the smear.